{"database":"biostudies-arrayexpress","file_versions":[],"scores":null,"additional":{"submitter":["Lars Hennig"],"organism":["Arabidopsis thaliana"],"software":["MicroArraySuite 5.0"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/E-TABM-1009"],"description":["Wild-type and rbr1-cs plants were grown on MS plates for 3 days. RNA was extracted from both genotypes and hybridized to ATH1 arrays."],"repository":["biostudies-arrayexpress"],"sample_protocol":["Hybridization - Title: Affymetrix Generic Hybridization. Description:","Growth Protocol - seedlings were grown for 3d on MS culture medium in growth chambers at 70% humidity and daily cycles of 16 h light and 8 h darkness at 22 C temperature.","Labeling - One-Cycle cDNA Synthesis Kit (Affymetrix, P/N 900431, Santa Clara, CA)"],"figure_sub":["MIAME Score","Raw Data","Organization","Assays and Data","MAGE-TAB Files","Array Designs"],"data_protocol":["Feature Extraction - Title: Affymetrix CEL analysis. Description:"],"omics_type":["Metabolomics","Unknown","Transcriptomics","Genomics","Proteomics"],"pubmed_abstract":["Seedling establishment is a crucial phase during plant development when the germinating heterotrophic embryo switches to autotrophic growth and development. Positive regulators of embryonic development need to be turned off, while the cell cycle machinery is activated to allow cell cycle entry and organ primordia initiation. However, it is not yet understood how the molecular mechanisms responsible for the onset of cell division, metabolism changes and cell differentiation are coordinated during this transition. Here, we demonstrate that the Arabidopsis thaliana RETINOBLASTOMA-RELATED protein (RBR) ortholog of the animal tumor suppressor retinoblastoma (pRB) not only controls the expression of cell cycle-related genes, but is also required for persistent shut-down of late embryonic genes b"],"study_type":["transcription profiling by array"],"species":["Arabidopsis thaliana"],"pubmed_title":["Plant RETINOBLASTOMA RELATED PROTEIN controls autotrophic seedling establishment"],"pubmed_authors":["Lars Hennig","Ruben Gutzat, Johannes Fütterer, Lorenzo Borghi, Sylvain Bischof, Yec’han Laizet, Lars Hennig, Regina Feil, John Lunn and Wilhelm Gruissem"],"additional_accession":[]},"is_claimable":false,"name":"Transcription profiling by array of Arabidopsis wild type and rbr1-cs plants","description":"Wild-type and rbr1-cs plants were grown on MS plates for 3 days. RNA was extracted from both genotypes and hybridized to ATH1 arrays.","dates":{"release":"2010-12-31T00:00:00Z","modification":"2022-03-10T07:30:51.849Z","creation":"2022-03-10T07:30:51.849Z"},"accession":"E-TABM-1009","cross_references":{"pubmed":["21693514"],"EFO":["EFO_0002768"],"doi":["10.1242/dev.060830"]}}