{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["20(5)"],"submitter":["Pena-Vazquez O"],"pubmed_abstract":["<h4>Background</h4>CrossFit is known as a functional fitness training high-intensity exercise to improve physical performance. The most studied polymorphisms are the ACTN3 R577X gene, known for speed, power, and strength, and ACE I/D, related to endurance and strength. The present investigation analyzed the effects of training on ACTN3 and ACE gene expression in CrossFit athletes for 12 weeks.<h4>Methods</h4>the studies included 18 athletes from the Rx category, where ACTN3 (RR, RX, XX) and ACE (II, ID, DD) characterization of genotypes and tests of maximum strength (NSCA), power (T-Force), and aerobic endurance (Course Navette) were performed. The technique used was the reverse transcription-quantitative PCR real-time polymerase chain reaction (RT-qPCR) for the relative expression analysi"],"journal":["International journal of environmental research and public health"],"pagination":["4404"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10001917"],"repository":["biostudies-literature"],"pubmed_title":["Prevalence of Polymorphism and Post-Training Expression of ACTN3 (R/X) and ACE (I/D) Genes in CrossFit Athletes."],"pmcid":["PMC10001917"],"pubmed_authors":["Cervantes Hernandez N","Pena-Vazquez O","Guereca-Arvizuo J","Enriquez-Del Castillo LA","Gonzalez-Chavez SA","Pacheco-Tena C","Candia Lujan R","Carrasco Legleu CE"],"additional_accession":[]},"is_claimable":false,"name":"Prevalence of Polymorphism and Post-Training Expression of ACTN3 (R/X) and ACE (I/D) Genes in CrossFit Athletes.","description":"<h4>Background</h4>CrossFit is known as a functional fitness training high-intensity exercise to improve physical performance. The most studied polymorphisms are the ACTN3 R577X gene, known for speed, power, and strength, and ACE I/D, related to endurance and strength. The present investigation analyzed the effects of training on ACTN3 and ACE gene expression in CrossFit athletes for 12 weeks.<h4>Methods</h4>the studies included 18 athletes from the Rx category, where ACTN3 (RR, RX, XX) and ACE (II, ID, DD) characterization of genotypes and tests of maximum strength (NSCA), power (T-Force), and aerobic endurance (Course Navette) were performed. The technique used was the reverse transcription-quantitative PCR real-time polymerase chain reaction (RT-qPCR) for the relative expression analysi","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Mar","modification":"2025-04-26T14:05:42.114Z","creation":"2024-11-09T23:43:45.214Z"},"accession":"S-EPMC10001917","cross_references":{"pubmed":["36901413"],"doi":["10.3390/ijerph20054404"]}}