{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Balaji V"],"funding":["Bill & Melinda Gates Foundation","FIC NIH HHS","NIAID NIH HHS","NIH HHS"],"pagination":["1213"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10005232"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(5)"],"pubmed_abstract":["The profile of the intestinal microbiota is known to be altered in malnourished young children in low- and middle-income countries. However, there are limited studies longitudinally evaluating the intestinal microbiota in malnourished young children in resource-limited settings over the first two years of life. In this longitudinal pilot study, we determined the effect of age, residential location, and intervention on the composition, relative abundance, and diversity of the intestinal microbiota in a representative sample of children under 24 months of age with no diarrhea in the preceding 72 h in the urban and rural areas of Sindh, Pakistan nested within a cluster-randomized trial evaluating the effect of zinc and micronutrients on growth and morbidity (ClinicalTrials.gov Identifier: NCT"],"journal":["Nutrients"],"pubmed_title":["Longitudinal Analysis of the Intestinal Microbiota among a Cohort of Children in Rural and Urban Areas of Pakistan."],"pmcid":["PMC10005232"],"funding_grant_id":["N/A","D43 TW009377","T32 AI007389","5T32 AI007389","D43 TW007392"],"pubmed_authors":["Chatterjee M","Wanke CA","Bhutta ZA","Rizvi A","Babji S","Naumova EN","Moy J","Soofi S","Ahmed I","Duara J","Balaji V","Dinh DM","Ward HD","Kane AV"],"additional_accession":[]},"is_claimable":false,"name":"Longitudinal Analysis of the Intestinal Microbiota among a Cohort of Children in Rural and Urban Areas of Pakistan.","description":"The profile of the intestinal microbiota is known to be altered in malnourished young children in low- and middle-income countries. However, there are limited studies longitudinally evaluating the intestinal microbiota in malnourished young children in resource-limited settings over the first two years of life. In this longitudinal pilot study, we determined the effect of age, residential location, and intervention on the composition, relative abundance, and diversity of the intestinal microbiota in a representative sample of children under 24 months of age with no diarrhea in the preceding 72 h in the urban and rural areas of Sindh, Pakistan nested within a cluster-randomized trial evaluating the effect of zinc and micronutrients on growth and morbidity (ClinicalTrials.gov Identifier: NCT","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2026-04-08T13:25:57.883Z","creation":"2024-11-05T15:05:43.127Z"},"accession":"S-EPMC10005232","cross_references":{"pubmed":["36904212"],"doi":["10.3390/nu15051213"]}}