biostudies-literatureUnknown10Ranilla LGThe high maize (<i>Zea mays L.</i>) diversity in Peru has been recognized worldwide, but the investigation focused on its integral health-relevant and bioactive characterization is limited. Therefore, this research aimed at studying the variability of the primary and the secondary (free and dietary fiber-bound phenolic, and carotenoid compounds) metabolites of three maize types (white, red, and orange) from the Peruvian Andean race <i>Cabanita</i> at different maturity stages (milk-S1, dough-S2, and mature-S3) using targeted and untargeted methods. In addition, their antioxidant potential, and α-amylase and α-glucosidase inhibitory activities relevant for hyperglycemia management were investigated using <i>in vitro</i> models. Results revealed a high effect of the maize type and the maturiFrontiers in nutrition1132228https://www.ebi.ac.uk/biostudies/studies/S-EPMC10011086biostudies-literatureIntegrated metabolite analysis and health-relevant <i>in vitro</i> functionality of white, red, and orange maize (<i>Zea mays</i> L.) from the Peruvian Andean race <i>Cabanita</i> at different maturity stages.PMC10011086Afaray-Carazas AVera-Vega MHuanuqueno HBegazo-Gutierrez HShetty KRanilla LGZolla GPedreschi RChirinos RfalseIntegrated metabolite analysis and health-relevant <i>in vitro</i> functionality of white, red, and orange maize (<i>Zea mays</i> L.) from the Peruvian Andean race <i>Cabanita</i> at different maturity stages.The high maize (<i>Zea mays L.</i>) diversity in Peru has been recognized worldwide, but the investigation focused on its integral health-relevant and bioactive characterization is limited. Therefore, this research aimed at studying the variability of the primary and the secondary (free and dietary fiber-bound phenolic, and carotenoid compounds) metabolites of three maize types (white, red, and orange) from the Peruvian Andean race <i>Cabanita</i> at different maturity stages (milk-S1, dough-S2, and mature-S3) using targeted and untargeted methods. In addition, their antioxidant potential, and α-amylase and α-glucosidase inhibitory activities relevant for hyperglycemia management were investigated using <i>in vitro</i> models. Results revealed a high effect of the maize type and the maturi2023-01-01T00:00:00Z20232026-07-14T20:12:51.831Z2025-08-17T03:07:31.949ZS-EPMC100110863692596310.3389/fnut.2023.1132228