{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["38(3)"],"submitter":["Arthursson H"],"pubmed_abstract":["<h4>Background</h4>Rewarming on cardiopulmonary bypass (CPB) is associated with increased metabolic demands; however, it remains unclear whether cerebral autoregulation is affected during this phase. This RCT aims to describe the effects of 20% supranormal, compared to normal CPB flow, on monitoring signs of inadequate perfusion, oxygenation, and disturbed cerebral autoregulation, during the rewarming phase of CPB.<h4>Method</h4>Thirty two patients scheduled for coronary artery bypass grafting were allocated to a Control group (<i>n</i> = 16) receiving a CPB pump flow corresponding to preoperatively measured cardiac output, and an Intervention group (<i>n</i> = 16) receiving the corresponding CPB pump flow increased by 20% during rewarming. Cerebral Oximetry Index (COx) was calculated with"],"journal":["Perfusion"],"pagination":["523-529"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10026164"],"repository":["biostudies-literature"],"pubmed_title":["Cerebral oxygenation and autoregulation during rewarming on cardiopulmonary bypass."],"pmcid":["PMC10026164"],"pubmed_authors":["Lennmyr F","Arthursson H","Tovedal T","Kjellberg G"],"additional_accession":[]},"is_claimable":false,"name":"Cerebral oxygenation and autoregulation during rewarming on cardiopulmonary bypass.","description":"<h4>Background</h4>Rewarming on cardiopulmonary bypass (CPB) is associated with increased metabolic demands; however, it remains unclear whether cerebral autoregulation is affected during this phase. This RCT aims to describe the effects of 20% supranormal, compared to normal CPB flow, on monitoring signs of inadequate perfusion, oxygenation, and disturbed cerebral autoregulation, during the rewarming phase of CPB.<h4>Method</h4>Thirty two patients scheduled for coronary artery bypass grafting were allocated to a Control group (<i>n</i> = 16) receiving a CPB pump flow corresponding to preoperatively measured cardiac output, and an Intervention group (<i>n</i> = 16) receiving the corresponding CPB pump flow increased by 20% during rewarming. Cerebral Oximetry Index (COx) was calculated with","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Apr","modification":"2025-04-04T08:40:07.101Z","creation":"2025-04-04T08:40:07.101Z"},"accession":"S-EPMC10026164","cross_references":{"pubmed":["35038948"],"doi":["10.1177/02676591211064961"]}}