{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Johnson DB"],"funding":["Melanoma Research Foundation","NCI NIH HHS"],"pagination":["265"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10033295"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(1)"],"pubmed_abstract":["<h4>Introduction</h4>COVID-19 particularly impacted patients with co-morbid conditions, including cancer. Patients with melanoma have not been specifically studied in large numbers. Here, we sought to identify factors that associated with COVID-19 severity among patients with melanoma, particularly assessing outcomes of patients on active targeted or immune therapy.<h4>Methods</h4>Using the COVID-19 and Cancer Consortium (CCC19) registry, we identified 307 patients with melanoma diagnosed with COVID-19. We used multivariable models to assess demographic, cancer-related, and treatment-related factors associated with COVID-19 severity on a 6-level ordinal severity scale. We assessed whether treatment was associated with increased cardiac or pulmonary dysfunction among hospitalized patients a"],"journal":["BMC cancer"],"pubmed_title":["Impact of COVID-19 in patients on active melanoma therapy and with history of melanoma."],"pmcid":["PMC10033295"],"funding_grant_id":["K12 CA090625"],"pubmed_authors":["Bekaii-Saab TS","Jhawar SR","Reynolds KL","Mico V","Demetri GD","Tejwani S","O'Connor TE","Balanchivadze N","Schmidt AL","Bardia A","Williams C","Goldsmith KJ","Rock CD","Van Loon S","Riaz IB","Fecher LA","Zaren HA","Mavromatis BH","Fu JC","LoRusso P","Egan PC","Monahan RS","Fazio A","Misdary CF","Bilen MA","Revankar SG","Masters T","Vilar-Compte D","Shah SA","Matar S","Khaki AR","Boldt A","Accordino MK","Advani PG","Smits M","Nohria A","Xu W","Castellano CA","Enriquez KT","Ferrario C","Schroeder BA","Boland G","Freeman DA","Labaki C","Gill DM","Griffiths EA","Blau EGRS","Lammers PE","Panasci J","Li A","Ramirez A","Dutra MS","Clement JM","Deeken JF","Duma N","Nelson HH","Williamson SP","Sueyoshi MH","Lyman GH","Wall S","Latif T","Gupta S","Hsu E","Farmakiotis D","Batist G","Ravindranathan D","Mishra S","Jha A","Yoon JJ","Halabi S","Alimohamed SI","Atkins MB","Mandapakala C","Gulati S","Berg S","Fahey CC","Ahluwalia MS","Nagaraj G","Rivera AV","Vinayak S","Kligerman S","Huber KE","Sachs Z","Beeghly-Fadiel A","Awosika J","Philip J","Bhatt PS","Smith SJ","Hausrath D","Yu PP","Andermann TM","Stover DG","Grivas P","Gulati AP","Kwon DH","Del Prete SA","Bashir B","Klein EJ","Wagner MJ","Faller B","Bouganim N","Gadgeel SM","Elkrief A","Lemmon CA","Ruiz-Garcia E","Wang LL","Carducci TM","Zhou AY","Hsiao A","Gillaspie EA","Fiala MA","Schapira L","Durbin EB","Morgans AK","Schwartz GK","Hennessy C","Cabebe EC","Li X","Friese CR","Reuben DY","Thomson CC","Singh SRK","Tachiki L","Croessmann S","Hayes-Lattin B","Bar MH","Connors JM","Yeh A","Low CA","Jensen C","Addison D","Van Allen EM","Feldman LE","Jayaraj A","Grover P","Vega-Luna K","Lustberg MB","Kasi A","Butt O","Lo KMS","COVID-19 and Cancer Consortium","Akhtari M","Choueiri TK","Serrano OK","Galsky MD","Lewis GC","Venepalli NK","McNair C","Kharofa J","Zhang T","Ajmera A","Hwang C","Rhodes TD","Polimera HV","Topaloglu U","Olszewski AJ","Dailey ME","Kulkarni AA","Gantt G","Tucker MD","Marcum M","Zamulko O","Rose SJ","Schweizer MT","Ingham MA","Bernicker EH","Shah S","Lynch RC","Rosovsky RP","Zhang S","Reid SA","Kloecker G","Huynh-Le MP","Wood WA","Sharifi N","Puc M","Nguyen RH","Peddi P","Brouha SS","Ahmad SA","Zubiri L","Dawsey SJ","Jani C","Bakouny Z","Glover MJ","Weinstein PL","Elias R","Slosky DA","Mushtaq S","Cook E","Wulff-Burchfield E","Wise-Draper T","Reeves ME","Hoppenot C","Shafer D","Desai A","Riely GJ","Warner JL","Mahmood SZ","Miller WH","Shah MR","Bijjula RR","Pomerantz LD","Bhutani D","Wu JT","Edwin NC","Koshkin VS","Halfdanarson TR","Belenkaya R","Rubinstein SM","Aboulafiam DM","Zaman QU","Karivedu V","Cheng A","Wise-Draper TM","Arvanitis P","Geiger CL","Hoskins KF","Pasquinelli M","Johnson DB","Henderson JP","Vinh DC","Wotman M","Saliby RM","Weissman LB","Menendez AG","Smith KE","Giordano A","Hafez N","Solorzano CC","Hawley JE","Goyal S","Rosen LR","Nemecek ER","Logan BB","Castillo DR","Gainor JF","Mashru SH","Loggers ET","Herbst R","Stockerl-Goldstein KE","Liu LC","Doroshow DB","McWeeney S","McCollough BB","Lewis MA","Vieira K","McKay RR","Mariano MG","Mansoor AH","Viera K","Hershman D","Small EJ","Brown AJ","Jabbour SK","Alexander M","Chen JL","Choi S","Schwartz C","Nakasone ES","Gatti-Mays ME","Cohen AM","Sohal DPS","Graber JJ","Abbasi SH","Bowles DW","Joshi M","Palmer JD","Zon RL","Stratton J","Davis EJ","Rovito MA","Knox N","Dzimitrowicz H","Weissmann LB","Borno HT","Nonato TK","Moore JK","Williams NO","Daher A","Stratton C","Khan H","French B","Khan M","Flora DB","Lau E","Nizam A","Pennell NA","Puzanov I","Heilman H"],"additional_accession":[]},"is_claimable":false,"name":"Impact of COVID-19 in patients on active melanoma therapy and with history of melanoma.","description":"<h4>Introduction</h4>COVID-19 particularly impacted patients with co-morbid conditions, including cancer. Patients with melanoma have not been specifically studied in large numbers. Here, we sought to identify factors that associated with COVID-19 severity among patients with melanoma, particularly assessing outcomes of patients on active targeted or immune therapy.<h4>Methods</h4>Using the COVID-19 and Cancer Consortium (CCC19) registry, we identified 307 patients with melanoma diagnosed with COVID-19. We used multivariable models to assess demographic, cancer-related, and treatment-related factors associated with COVID-19 severity on a 6-level ordinal severity scale. We assessed whether treatment was associated with increased cardiac or pulmonary dysfunction among hospitalized patients a","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Mar","modification":"2025-04-22T12:02:28.917Z","creation":"2024-11-20T23:16:28.243Z"},"accession":"S-EPMC10033295","cross_references":{"pubmed":["36949413"],"doi":["10.1186/s12885-023-10708-6"]}}