{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["McCarthy C"],"funding":["NHLBI NIH HHS"],"pagination":["207-219"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10037558"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["81(3)"],"pubmed_abstract":["<h4>Background</h4>Few data exist regarding the implementation of high-sensitivity cardiac troponin (hs-cTn) assays in the United States since their approval.<h4>Objectives</h4>This study sought to explore trends in hs-cTn assay implementation over time and assess the association of their use with in-hospital cardiac testing and outcomes.<h4>Methods</h4>The study examined trends in implementation of hs-cTn assays among participating hospitals in the National Cardiovascular Data Registry Chest Pain-MI [Myocardial Infarction] Registry from January 1, 2019 through September 30, 2021. Associations among hs-cTn use, use of in-hospital diagnostic imaging, and patient outcomes were assessed using generalized estimating equation models with logistic or gamma distributions.<h4>Results</h4>Among 550"],"journal":["Journal of the American College of Cardiology"],"pubmed_title":["Implementation of High-Sensitivity Cardiac Troponin Assays in the United States."],"pmcid":["PMC10037558"],"funding_grant_id":["K23 HL150315","T32 HL094301"],"pubmed_authors":["Wang TY","de Lemos JA","Jaffe AS","Sandoval Y","Januzzi JL","Raber I","Li S","Wasfy JH","Apple FS","Newby LK","Kontos MC","Smilowitz NR","Pandey A","Daniels LB","McCarthy C"],"additional_accession":[]},"is_claimable":false,"name":"Implementation of High-Sensitivity Cardiac Troponin Assays in the United States.","description":"<h4>Background</h4>Few data exist regarding the implementation of high-sensitivity cardiac troponin (hs-cTn) assays in the United States since their approval.<h4>Objectives</h4>This study sought to explore trends in hs-cTn assay implementation over time and assess the association of their use with in-hospital cardiac testing and outcomes.<h4>Methods</h4>The study examined trends in implementation of hs-cTn assays among participating hospitals in the National Cardiovascular Data Registry Chest Pain-MI [Myocardial Infarction] Registry from January 1, 2019 through September 30, 2021. Associations among hs-cTn use, use of in-hospital diagnostic imaging, and patient outcomes were assessed using generalized estimating equation models with logistic or gamma distributions.<h4>Results</h4>Among 550","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2025-04-03T23:49:51.829Z","creation":"2025-04-03T23:49:51.829Z"},"accession":"S-EPMC10037558","cross_references":{"pubmed":["36328155"],"doi":["10.1016/j.jacc.2022.10.017"]}}