{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Senner F"],"funding":["European Union’s Horizon 2020 Research Innovation Programme","Deutsche Forschungsgemeinschaft","2016 NARSAD Young Investigator Grant","Dr. Lisa Oehler Foundation","Munich Clinician Scientist Program"],"pagination":["99"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10039892"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(1)"],"pubmed_abstract":["Existing guidelines recommend psychopharmacological treatment for the management of schizophrenia and bipolar disorder as part of holistic treatment concepts. About half of the patients do not take their medication regularly, although treatment adherence can prevent exacerbations and re-hospitalizations. To date, the relationship between medication adherence and cognitive performance is understudied. Therefore, this study investigated the relationship between medication adherence and cognitive performance by analyzing the data of 862 participants with schizophrenia-spectrum and bipolar disorders (mean [SD] age, 41.9 [12.48] years; 44.8% female) from a multicenter study (PsyCourse Study). Z-scores for three cognitive domains were calculated, global functioning was measured with the Global A"],"journal":["Translational psychiatry"],"pubmed_title":["Medication adherence and cognitive performance in schizophrenia-spectrum and bipolar disorder: results from the PsyCourse Study."],"pmcid":["PMC10039892"],"funding_grant_id":["SCHU 1603/4-1, 5-1, 7-1; FA241/16-1"],"pubmed_authors":["Hasan A","Heilbronner M","Anghelescu IG","Reininghaus EZ","Baune BT","Zimmermann J","Senner F","Dietrich DE","Kohshour MO","Budde M","Schaupp SK","Bengesser S","Reich-Erkelenz D","Spitzer C","Falkai P","Dalkner N","Fallgatter AJ","Senner S","Reimer J","Schmauß M","Jager M","Hiendl L","Schulte EC","Adorjan K","Papiol S","Juckel G","Schulze TG","Dannlowski U","Kalman JL","Kirchner SK","Heilbronner U","Konrad C","Vogl T"],"additional_accession":[]},"is_claimable":false,"name":"Medication adherence and cognitive performance in schizophrenia-spectrum and bipolar disorder: results from the PsyCourse Study.","description":"Existing guidelines recommend psychopharmacological treatment for the management of schizophrenia and bipolar disorder as part of holistic treatment concepts. About half of the patients do not take their medication regularly, although treatment adherence can prevent exacerbations and re-hospitalizations. To date, the relationship between medication adherence and cognitive performance is understudied. Therefore, this study investigated the relationship between medication adherence and cognitive performance by analyzing the data of 862 participants with schizophrenia-spectrum and bipolar disorders (mean [SD] age, 41.9 [12.48] years; 44.8% female) from a multicenter study (PsyCourse Study). Z-scores for three cognitive domains were calculated, global functioning was measured with the Global A","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Mar","modification":"2025-04-26T13:10:53.903Z","creation":"2025-04-06T14:08:43.598Z"},"accession":"S-EPMC10039892","cross_references":{"pubmed":["36966169"],"doi":["10.1038/s41398-023-02373-x"]}}