biostudies-literatureUnknown10Wang BDilated cardiomyopathy (DCM) is one of the leading causes of heart failure in children with diverse clinical characteristics. To date, DCM with a giant atrium as the first manifestation is rare and has not been reported in previous literature. We report a case of a male infant born with a significantly enlarged right atrium. Due to worsened clinical symptoms and the risk of arrhythmias and thrombosis, we performed the surgical reduction of the right atrium. Unfortunately, DCM and a progressive re-enlargement of the right atrium appeared during midterm follow-up. The mother's echocardiogram also suggested DCM, and the patient was eventually considered for a diagnosis of familial DCM. This case may expand the clinical spectrum of DCM and reminds us of the importance of good follow-up of chilFrontiers in cardiovascular medicine1083188https://www.ebi.ac.uk/biostudies/studies/S-EPMC10050595biostudies-literatureGiant right atrium in a child with dilated cardiomyopathy: A case report.PMC10050595Shan GBing ZLi ZWang BZhang QXing QfalseGiant right atrium in a child with dilated cardiomyopathy: A case report.Dilated cardiomyopathy (DCM) is one of the leading causes of heart failure in children with diverse clinical characteristics. To date, DCM with a giant atrium as the first manifestation is rare and has not been reported in previous literature. We report a case of a male infant born with a significantly enlarged right atrium. Due to worsened clinical symptoms and the risk of arrhythmias and thrombosis, we performed the surgical reduction of the right atrium. Unfortunately, DCM and a progressive re-enlargement of the right atrium appeared during midterm follow-up. The mother's echocardiogram also suggested DCM, and the patient was eventually considered for a diagnosis of familial DCM. This case may expand the clinical spectrum of DCM and reminds us of the importance of good follow-up of chil2023-01-01T00:00:00Z20232026-05-29T00:10:46.582Z2025-02-19T00:14:04.748ZS-EPMC100505953700832610.3389/fcvm.2023.1083188