biostudies-literatureUnknown18(3)Schwarzwald A<h4>Background and purpose</h4>Limited data is available on sex differences in young stroke patients describing discrepant findings. This study aims to investigate the sex differences in young stroke patients.<h4>Methods</h4>Prospective cohort study comparing risk factors, etiology, stroke localization, severity on admission, management and outcome in patients aged 16-55 years with acute ischemic stroke consecutively included in the Bernese stroke database between 01/2015 to 12/2018 with subgroup analyses for very young (16-35y) and young patients (36-55y).<h4>Results</h4>689 patients (39% female) were included. Stroke in women dominated in the very young (53.8%, p<0.001) and in men in the young (63.9%, p<0.001). As risk factors only sleep-disordered breathing was more predominant in men iPloS onee0274722https://www.ebi.ac.uk/biostudies/studies/S-EPMC10065293biostudies-literatureImpact of sex in stroke in the young.PMC10065293Fischer UArnold MGoeggel Simonetti BDobrocky TScutelnic ASeiffge DMeinel TRMordasini PSchwarzwald AGralla JHeldner MRUmarova RKaesmacher JJung SBeyeler MfalseImpact of sex in stroke in the young.<h4>Background and purpose</h4>Limited data is available on sex differences in young stroke patients describing discrepant findings. This study aims to investigate the sex differences in young stroke patients.<h4>Methods</h4>Prospective cohort study comparing risk factors, etiology, stroke localization, severity on admission, management and outcome in patients aged 16-55 years with acute ischemic stroke consecutively included in the Bernese stroke database between 01/2015 to 12/2018 with subgroup analyses for very young (16-35y) and young patients (36-55y).<h4>Results</h4>689 patients (39% female) were included. Stroke in women dominated in the very young (53.8%, p<0.001) and in men in the young (63.9%, p<0.001). As risk factors only sleep-disordered breathing was more predominant in men i2023-01-01T00:00:00Z20232025-04-26T19:39:42.855Z2025-04-06T16:09:09.542ZS-EPMC100652933700078810.1371/journal.pone.0274722