{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lai Y"],"funding":["Shandong Provincial Key Research and Development Program","Shandong Province Agricultural Major Applied Technology Innovation Project"],"pagination":["59"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10071666"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(1)"],"pubmed_abstract":["<h4>Background</h4>Keratin, the main component of chicken feather, is the third most abundant material after cellulose and chitin. Keratin can be converted into high-value compounds and is considered a potential high-quality protein supplement; However, its recalcitrance makes its breakdown a challenge, and the mechanisms of action of keratinolytic proteases-mediated keratinous substrates degradation are not yet fully elucidated. Bacillus sp. CN2, having many protease-coding genes, is a dominant species in keratin-rich materials environments. To explore the degradation patterns of feather keratin, in this study, we investigated the characteristics of feather degradation by strain CN2 based on the functional-degradomics technology.<h4>Results</h4>Bacillus sp. CN2 showed strong feather kerat"],"journal":["Biotechnology for biofuels and bioproducts"],"pubmed_title":["Insights into the keratin efficient degradation mechanism mediated by Bacillus sp. CN2 based on integrating functional degradomics."],"pmcid":["PMC10071666"],"funding_grant_id":["SD2019ZZ018","2021CXGC010803"],"pubmed_authors":["Li W","Lai Y","Zheng X","Wu X","Wang L"],"additional_accession":[]},"is_claimable":false,"name":"Insights into the keratin efficient degradation mechanism mediated by Bacillus sp. CN2 based on integrating functional degradomics.","description":"<h4>Background</h4>Keratin, the main component of chicken feather, is the third most abundant material after cellulose and chitin. Keratin can be converted into high-value compounds and is considered a potential high-quality protein supplement; However, its recalcitrance makes its breakdown a challenge, and the mechanisms of action of keratinolytic proteases-mediated keratinous substrates degradation are not yet fully elucidated. Bacillus sp. CN2, having many protease-coding genes, is a dominant species in keratin-rich materials environments. To explore the degradation patterns of feather keratin, in this study, we investigated the characteristics of feather degradation by strain CN2 based on the functional-degradomics technology.<h4>Results</h4>Bacillus sp. CN2 showed strong feather kerat","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Apr","modification":"2025-04-22T13:07:28.572Z","creation":"2024-11-12T16:41:57.362Z"},"accession":"S-EPMC10071666","cross_references":{"pubmed":["37016453"],"doi":["10.1186/s13068-023-02308-0"]}}