biostudies-literatureUnknown24(4)Otten MH<h4>Objectives</h4>To investigate neurocognitive, psychosocial, and quality of life (QoL) outcomes in children with Multisystem Inflammatory Syndrome in Children (MIS-C) seen 3-6 months after PICU admission.<h4>Design</h4>National prospective cohort study March 2020 to November 2021.<h4>Setting</h4>Seven PICUs in the Netherlands.<h4>Patients</h4>Children with MIS-C (0-17 yr) admitted to a PICU.<h4>Interventions</h4>None.<h4>Measurements and main results</h4>Children and/or parents were seen median (interquartile range [IQR] 4 mo [3-5 mo]) after PICU admission. Testing included assessment of neurocognitive, psychosocial, and QoL outcomes with reference to Dutch pre-COVID-19 general population norms. Effect sizes (Hedges' g ) were used to indicate the strengths and clinical relevance of diffPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies289-300https://www.ebi.ac.uk/biostudies/studies/S-EPMC10072052biostudies-literatureNeurocognitive, Psychosocial, and Quality of Life Outcomes After Multisystem Inflammatory Syndrome in Children Admitted to the PICU.PMC10072052Otten MHRoeleveld PPKneyber MCJBuddingh EPvan Schooneveld MBuysse CMPHumblet MWalker JCvon Asmuth EGJKetharanathan NKrabben Gvan Woensel JBMHogenbirk KWassenberg Rvan Zwol ADulfer KMaebe Svan Waardenburg DMaas NMde Wit Ede Hoog MTerheggen-Lagro SWJHaverman LTimmers-Raaijmaakers BOostrom KJJoosten KFMde Sonnaville ESVBunker-Wiersma HEKnoester HLemson JWolthuis DWfalseNeurocognitive, Psychosocial, and Quality of Life Outcomes After Multisystem Inflammatory Syndrome in Children Admitted to the PICU.<h4>Objectives</h4>To investigate neurocognitive, psychosocial, and quality of life (QoL) outcomes in children with Multisystem Inflammatory Syndrome in Children (MIS-C) seen 3-6 months after PICU admission.<h4>Design</h4>National prospective cohort study March 2020 to November 2021.<h4>Setting</h4>Seven PICUs in the Netherlands.<h4>Patients</h4>Children with MIS-C (0-17 yr) admitted to a PICU.<h4>Interventions</h4>None.<h4>Measurements and main results</h4>Children and/or parents were seen median (interquartile range [IQR] 4 mo [3-5 mo]) after PICU admission. Testing included assessment of neurocognitive, psychosocial, and QoL outcomes with reference to Dutch pre-COVID-19 general population norms. Effect sizes (Hedges' g ) were used to indicate the strengths and clinical relevance of diff2023-01-01T00:00:00Z2023 Apr2025-04-04T10:41:36.631Z2025-04-04T10:41:36.631ZS-EPMC100720523668868810.1097/PCC.0000000000003180