biostudies-literatureUnknown14Skalniak A<h4>Introduction</h4>The standard care of schizophrenia patients is based on the assessment of their psychotic behavior, using interview-based, subjective scales that measure symptoms severity. We aimed at defining easily accessible and inexpensive blood-derived clinical diagnostic parameters that might serve as objective markers in the prediction of the effects of pharmacological treatment of schizophrenia patients.<h4>Methods</h4>A total of 40 patients with schizophrenia diagnosis according to ICD 10 during psychotic decompensation were included in the study. Blood-based biochemical parameters, BMI and interview-based medical scales of symptom severity were determined - all at admission and after 12 weeks of standard pharmacological treatment.<h4>Results</h4>The drops in scale values werFrontiers in psychiatry1082135https://www.ebi.ac.uk/biostudies/studies/S-EPMC10073498biostudies-literatureImmunological routine laboratory parameters at admission influence the improvement of positive symptoms in schizophrenia patients after pharmacological treatment.PMC10073498Pilecki MDonicz PSmierciak NKrzysciak WSzwajca MSkalniak AKozicz TfalseImmunological routine laboratory parameters at admission influence the improvement of positive symptoms in schizophrenia patients after pharmacological treatment.<h4>Introduction</h4>The standard care of schizophrenia patients is based on the assessment of their psychotic behavior, using interview-based, subjective scales that measure symptoms severity. We aimed at defining easily accessible and inexpensive blood-derived clinical diagnostic parameters that might serve as objective markers in the prediction of the effects of pharmacological treatment of schizophrenia patients.<h4>Methods</h4>A total of 40 patients with schizophrenia diagnosis according to ICD 10 during psychotic decompensation were included in the study. Blood-based biochemical parameters, BMI and interview-based medical scales of symptom severity were determined - all at admission and after 12 weeks of standard pharmacological treatment.<h4>Results</h4>The drops in scale values wer2023-01-01T00:00:00Z20232025-04-05T12:18:30.249Z2025-04-05T12:18:30.249ZS-EPMC100734983703295110.3389/fpsyt.2023.1082135