{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Adviento BA"],"funding":["GlaxoSmithKline","COPD Foundation","Novartis Pharmaceuticals Corporation","National Heart, Lung, and Blood Institute","NHLBI NIH HHS"],"pagination":["292-302"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10083129"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["163(2)"],"pubmed_abstract":["<h4>Background</h4>Studies have shown that COPD and smoking are associated with increased suicide risk. To date, there are no prospective studies examining suicide risk among individuals with smoking exposure along a spectrum of pulmonary diseases ranging from normal spirometry to severe COPD.<h4>Research question</h4>Which clinical variables predict death by suicide or overdose of indeterminate intent in a large cohort of individuals with smoking exposure within the Genetic Epidemiology of COPD (COPDGene) study?<h4>Study design and methods</h4>We studied data from 9,930 participants involved in COPDGene, a multisite, prospective cohort study of individuals with smoking exposure. Primary cause of adjudicated deaths was identified by using death certificates, family reports, and medical rec"],"journal":["Chest"],"pubmed_title":["Clinical Markers Associated With Risk of Suicide or Drug Overdose Among Individuals With Smoking Exposure: A Longitudinal Follow-up Study of the COPDGene Cohort."],"pmcid":["PMC10083129"],"funding_grant_id":["U01 HL089897","NCT00608764","U01 HL089856"],"pubmed_authors":["Lan C","Kelsen S","Diaz AA","Ruiz ME","Kinney GL","D'Alonzo G","Morrow J","Charbonnier JP","Austin E","Rosiello R","Cordova F","Ross JC","Sanchez-Ferrero GV","Putcha N","Porszasz J","Vummidi D","Nardelli P","Thomashow B","Shinozaki G","Budoff M","Comellas AP","McEvoy C","Washko G","Jacobson FL","Soler X","Newell JD","Qiao D","Wendt C","Ponce M","Kunisaki KM","Billings J","Wells JM","Horton K","Bailey W","Sciurba F","Dass C","Kazerooni E","Regan EA","Judy PF","Hersh C","Dransfield M","Conrad D","Fischer H","Hayden LP","Kluiber A","Anzueto A","Yun J","Make BJ","Stringer W","Castaldi PJ","van Ginneken B","Washko GR","Nath H","Desai P","Silverman EK","Banaei-Kashani F","Barr RG","Maselli-Caceres D","Jacobs M","Newell J","Han MK","Yohannes AM","Beaty TH","MacIntyre N","Lynch DA","Schroeder J","Shenoy K","Lowe KE","Criner G","Hoffman EA","Notary A","Weissfeld J","Bon J","Make B","Ghosh A","Humphries S","Curtis JL","Lange C","Ciccolella D","Fiedorowicz JG","COPDGene Investigators","Van Beek E","Guntupalli K","Centeno JP","Westney G","Labaki W","Austin J","Stoel BC","Kim W","Veitel L","Adams S","Hersh CP","Wan ES","Tashjian J","Yen A","Kim V","Regan E","Galban CJ","Rossiter H","Vega-Sanchez ME","Hoth KF","Hetmanski J","Young KA","Allen T","Thompson B","Murray S","Wise R","Hansel NN","Laird N","Sieren J","Hokanson JE","Steiner RM","D'Souza B","Galban C","Guy E","Bhatt SP","Singh H","Sharafkhaneh A","Prokopenko D","Bowler RP","Kechris K","Adami A","Foreman MG","Pace D","Casaburi R","Hanania NA","Pernicano PG","Wilson CG","Saferali A","Flenaugh EL","San Jose Estepar R","Washington L","Mamary AJ","Parulekar A","Cho MH","Lutz SM","Khatiwada A","Pratte K","Bowler R","Strand M","Iyer A","Sakornsakolpat P","Lambert A","DeMeo DL","van Rikxoort E","Kinney G","Terpenning S","Coxson HO","Kazerooni EA","Hobbs BD","Boriek A","Adviento BA","Chandra D","Marchetti N","Iyer AS","Crapo JD","Satti A","Begnaud A","Moll M","Holm KE","Atik M","Tschirren J","Jensen R","McAdams HP","McDonald ML","Bell B","Crooks J","Hanania N","Gebrekristos H","Swift I","Swift A","El Boueiz A","Oh A","Brown R"],"additional_accession":[]},"is_claimable":false,"name":"Clinical Markers Associated With Risk of Suicide or Drug Overdose Among Individuals With Smoking Exposure: A Longitudinal Follow-up Study of the COPDGene Cohort.","description":"<h4>Background</h4>Studies have shown that COPD and smoking are associated with increased suicide risk. To date, there are no prospective studies examining suicide risk among individuals with smoking exposure along a spectrum of pulmonary diseases ranging from normal spirometry to severe COPD.<h4>Research question</h4>Which clinical variables predict death by suicide or overdose of indeterminate intent in a large cohort of individuals with smoking exposure within the Genetic Epidemiology of COPD (COPDGene) study?<h4>Study design and methods</h4>We studied data from 9,930 participants involved in COPDGene, a multisite, prospective cohort study of individuals with smoking exposure. Primary cause of adjudicated deaths was identified by using death certificates, family reports, and medical rec","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-05T10:17:13.676Z","creation":"2025-04-05T10:17:13.676Z"},"accession":"S-EPMC10083129","cross_references":{"pubmed":["36167120"],"doi":["10.1016/j.chest.2022.09.022"]}}