biostudies-literatureUnknown61(49)Zhao FChina Scholarship CouncilHerein, we developed a new procedure on 1,2-dicarbonylative cyclization of 4-aryl-1-butenes with alkyl bromides. Using simple copper catalyst, two molecules of carbon monoxide were introduced into the double bond with the formation of four new C-C bonds and a new ring. Various α-tetralones and 2,3-dihydroquinolin-4-ones were formed in moderate to good yields.Angewandte Chemie (International ed. in English)e202214812https://www.ebi.ac.uk/biostudies/studies/S-EPMC10100518biostudies-literatureCopper-Catalyzed 1,2-Dicarbonylative Cyclization of Alkenes with Alkyl Bromides via Radical Cascade Process.PMC10100518Zhao FFranke RGu XWWu XFfalseCopper-Catalyzed 1,2-Dicarbonylative Cyclization of Alkenes with Alkyl Bromides via Radical Cascade Process.Herein, we developed a new procedure on 1,2-dicarbonylative cyclization of 4-aryl-1-butenes with alkyl bromides. Using simple copper catalyst, two molecules of carbon monoxide were introduced into the double bond with the formation of four new C-C bonds and a new ring. Various α-tetralones and 2,3-dihydroquinolin-4-ones were formed in moderate to good yields.2022-01-01T00:00:00Z2022 Dec2025-04-18T21:20:17.375Z2025-02-18T23:40:31.815ZS-EPMC101005183625479410.1002/anie.202214812