biostudies-literatureUnknownFan CNational Natural Science Foundation of ChinaMarine bivalves include species important globally for aquaculture and estuary ecology. However, epizootics of variable etiologies often pose a threat to the marine fishery industry and ecosystem by causing significant mortalities in related species. One of such diseases is larval vibriosis caused by bacteria of the genus <i>Vibrio</i>, which frequently occurs and causes mass mortalities in bivalve larvae and juveniles in hatcheries. During a mass mortality of razor clam, Sinonovacula constricta, juveniles in a shellfish hatchery in 2019, Vibrio mediterranei was identified as a dominant bacterial species in diseased animals and their rearing water. In this study, we selected and characterized 11 <i>V. mediterranei</i> isolates and studied their pathogenicity to the larvae and juveniles of Microbiology spectrume0492322https://www.ebi.ac.uk/biostudies/studies/S-EPMC10101119biostudies-literatureCharacterization of Vibrio mediterranei Isolates as Causative Agents of Vibriosis in Marine Bivalves.PMC1010111932202989Zhang HXue QDai WLiu SHe LXu HFan CfalseCharacterization of Vibrio mediterranei Isolates as Causative Agents of Vibriosis in Marine Bivalves.Marine bivalves include species important globally for aquaculture and estuary ecology. However, epizootics of variable etiologies often pose a threat to the marine fishery industry and ecosystem by causing significant mortalities in related species. One of such diseases is larval vibriosis caused by bacteria of the genus <i>Vibrio</i>, which frequently occurs and causes mass mortalities in bivalve larvae and juveniles in hatcheries. During a mass mortality of razor clam, Sinonovacula constricta, juveniles in a shellfish hatchery in 2019, Vibrio mediterranei was identified as a dominant bacterial species in diseased animals and their rearing water. In this study, we selected and characterized 11 <i>V. mediterranei</i> isolates and studied their pathogenicity to the larvae and juveniles of 2023-01-01T00:00:00Z2023 Feb2026-06-13T06:09:07.651Z2025-04-05T11:28:45.184ZS-EPMC101011193672841510.1128/spectrum.04923-22