biostudies-literatureUnknownOtto M<h4>Background</h4>COVID-19 pandemic research efforts have focused on disease phenotypes in adults. A distinct spectrum of illness has been documented in paediatric populations. We aimed to review paediatric intensive care unit (ICU) admissions in Australia, across differing variant predominant phases of the pandemic.<h4>Methods</h4>Data reported to the Short PeRiod IncideNce sTudy of Severe Acute Respiratory Infection (SPRINT-SARI) Australia, across 49 ICUs from February 2020 to June 2022 were extracted. We defined 'child' as patients aged <12 years, 'adolescent' as patients aged 12-17 years, and 'young adult' as patients aged 18-25 years.<h4>Findings</h4>We identified 226 paediatric ICU admissions with COVID-19, representing 3.9% of ICU admissions across the study period. Comorbidity wasThe Lancet regional health. Western Pacific100763https://www.ebi.ac.uk/biostudies/studies/S-EPMC10102812biostudies-literatureCOVID-19 related ICU admissions in paediatric and young adult patients in Australia: a national case series 2020-2022.PMC10102812Britton PNUdy AASerpa Neto ABurrell AJCFesta MErickson SOtto MCrawford NWSPRINT-SARI Australia InvestigatorsfalseCOVID-19 related ICU admissions in paediatric and young adult patients in Australia: a national case series 2020-2022.<h4>Background</h4>COVID-19 pandemic research efforts have focused on disease phenotypes in adults. A distinct spectrum of illness has been documented in paediatric populations. We aimed to review paediatric intensive care unit (ICU) admissions in Australia, across differing variant predominant phases of the pandemic.<h4>Methods</h4>Data reported to the Short PeRiod IncideNce sTudy of Severe Acute Respiratory Infection (SPRINT-SARI) Australia, across 49 ICUs from February 2020 to June 2022 were extracted. We defined 'child' as patients aged <12 years, 'adolescent' as patients aged 12-17 years, and 'young adult' as patients aged 18-25 years.<h4>Findings</h4>We identified 226 paediatric ICU admissions with COVID-19, representing 3.9% of ICU admissions across the study period. Comorbidity was2023-01-01T00:00:00Z2023 Apr2025-04-26T06:01:49.368Z2025-04-06T11:43:44.083ZS-EPMC101028123736086510.1016/j.lanwpc.2023.100763