{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2023"],"submitter":["Peng B"],"pubmed_abstract":["<h4>Background</h4>Necrotizing enterocolitis (NEC) and late-onset sepsis (LOS) are the major contributors to mortality and morbidity in preterm infants. This updated meta-analysis was aimed to assess the effects of mother's milk on the incidence of NEC, LOS, and other clinical outcomes in preterm infants.<h4>Methods</h4>PubMed, Embase, and the Cochrane library were searched for papers published up to October 2022.<h4>Results</h4>A total of 13 RCTs with 1330 infants were included in the final analysis. Significant difference in NEC (stage 2 or 3) was found between the intervention group and the control group (RR = 0.508, 95% CI: 0.314-0.822, and <i>P</i>=0.008). The incidence of proven LOS (RR = 0.809, 95% CI: 0.610-1.071, and <i>P</i>=0.139) and death (RR = 0.800, 95% CI: 0.571-1.122, and "],"journal":["Evidence-based complementary and alternative medicine : eCAM"],"pagination":["7378064"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10104743"],"repository":["biostudies-literature"],"pubmed_title":["Oral Application of Mother's Own Milk for Reducing Necrotizing Enterocolitis in Preterm Infants: An Updated Meta-Analysis of RCTs."],"pmcid":["PMC10104743"],"pubmed_authors":["Yu L","Qian J","Peng B","Zhang Y","Zheng B","Zhu C"],"additional_accession":[]},"is_claimable":false,"name":"Oral Application of Mother's Own Milk for Reducing Necrotizing Enterocolitis in Preterm Infants: An Updated Meta-Analysis of RCTs.","description":"<h4>Background</h4>Necrotizing enterocolitis (NEC) and late-onset sepsis (LOS) are the major contributors to mortality and morbidity in preterm infants. This updated meta-analysis was aimed to assess the effects of mother's milk on the incidence of NEC, LOS, and other clinical outcomes in preterm infants.<h4>Methods</h4>PubMed, Embase, and the Cochrane library were searched for papers published up to October 2022.<h4>Results</h4>A total of 13 RCTs with 1330 infants were included in the final analysis. Significant difference in NEC (stage 2 or 3) was found between the intervention group and the control group (RR = 0.508, 95% CI: 0.314-0.822, and <i>P</i>=0.008). The incidence of proven LOS (RR = 0.809, 95% CI: 0.610-1.071, and <i>P</i>=0.139) and death (RR = 0.800, 95% CI: 0.571-1.122, and ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-04T12:43:47.471Z","creation":"2025-04-04T12:43:47.471Z"},"accession":"S-EPMC10104743","cross_references":{"pubmed":["37064945"],"doi":["10.1155/2023/7378064"]}}