{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16(2)"],"submitter":["Buch J"],"funding":["Johnson and Johnson Vision Care"],"pubmed_abstract":["<h4>Purpose</h4>Evaluate the performance of a photochromic contact lens in various lighting conditions throughout the day, including those indoor and outdoor environments where the photochromic contact lens is in a less active or inactive state.<h4>Methods</h4>Data from two clinical trials of a photochromic contact lens were analyzed to evaluate its performance in various light environments. Both studies involved a photochromic test lens (ACUVUE® OASYS with Transitions™ Light Intelligent Technology™) and a similar non-photochromic control lens (ACUVUE® OASYS 2-week with HYDRACLEAR® PLUS). The studies were both multi-visit, multi-site, 2-treatment by 3-period randomized crossover (i.e., Test/Control/Control or Control/Test/Test) dispensing studies, with follow-up visits after each 2-week di"],"journal":["Journal of optometry"],"pagination":["135-142"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10104794"],"repository":["biostudies-literature"],"pubmed_title":["Unexpected vision performance with photochromic contact lenses in normal and low light conditions: An analysis of two randomized trials."],"pmcid":["PMC10104794"],"pubmed_authors":["Sonoda L","Cannon J","Buch J"],"additional_accession":[]},"is_claimable":false,"name":"Unexpected vision performance with photochromic contact lenses in normal and low light conditions: An analysis of two randomized trials.","description":"<h4>Purpose</h4>Evaluate the performance of a photochromic contact lens in various lighting conditions throughout the day, including those indoor and outdoor environments where the photochromic contact lens is in a less active or inactive state.<h4>Methods</h4>Data from two clinical trials of a photochromic contact lens were analyzed to evaluate its performance in various light environments. Both studies involved a photochromic test lens (ACUVUE® OASYS with Transitions™ Light Intelligent Technology™) and a similar non-photochromic control lens (ACUVUE® OASYS 2-week with HYDRACLEAR® PLUS). The studies were both multi-visit, multi-site, 2-treatment by 3-period randomized crossover (i.e., Test/Control/Control or Control/Test/Test) dispensing studies, with follow-up visits after each 2-week di","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Apr-Jun","modification":"2026-05-28T17:53:01.997Z","creation":"2025-04-04T14:30:38.134Z"},"accession":"S-EPMC10104794","cross_references":{"pubmed":["35953430"],"doi":["10.1016/j.optom.2022.06.004"]}}