{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Garcia-Hermoso A"],"funding":["Instituto de Salud Carlos III"],"pagination":["147-157"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10105032"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(2)"],"pubmed_abstract":["<h4>Background</h4>This study investigates the effects of exercise training on exerkines in patients with type 2 diabetes mellitus to determine the optimal exercise prescription.<h4>Methods</h4>A systematic search for relevant studies was performed in 3 databases. Randomized controlled trials investigating the effects of exercise training on at least one of the following exerkines were included: adiponectin, apelin, brain-derived neurotrophic factor, fetuin-A, fibroblast growth factor-21, follistatin, ghrelin, interleukin (IL)-6, IL-8, IL-10, IL-15, IL-18, leptin, myostatin, omentin, resistin, retinol-binding protein 4, tumor necrosis factor-α, and visfatin.<h4>Results</h4>Forty randomized controlled trials were selected for data extraction (n = 2160). Exercise training induces changes in "],"journal":["Journal of sport and health science"],"pubmed_title":["Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials."],"pmcid":["PMC10105032"],"funding_grant_id":["III – CP18/0150"],"pubmed_authors":["Diez J","Garcia-Hermoso A","Izquierdo M","Ramirez-Velez R","Gonzalez A"],"additional_accession":[]},"is_claimable":false,"name":"Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials.","description":"<h4>Background</h4>This study investigates the effects of exercise training on exerkines in patients with type 2 diabetes mellitus to determine the optimal exercise prescription.<h4>Methods</h4>A systematic search for relevant studies was performed in 3 databases. Randomized controlled trials investigating the effects of exercise training on at least one of the following exerkines were included: adiponectin, apelin, brain-derived neurotrophic factor, fetuin-A, fibroblast growth factor-21, follistatin, ghrelin, interleukin (IL)-6, IL-8, IL-10, IL-15, IL-18, leptin, myostatin, omentin, resistin, retinol-binding protein 4, tumor necrosis factor-α, and visfatin.<h4>Results</h4>Forty randomized controlled trials were selected for data extraction (n = 2160). Exercise training induces changes in ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Mar","modification":"2025-05-18T11:13:05.368Z","creation":"2025-05-18T11:13:05.368Z"},"accession":"S-EPMC10105032","cross_references":{"pubmed":["36351545"],"doi":["10.1016/j.jshs.2022.11.003"]}}