biostudies-literatureUnknown10Tseng HY<h4>Background and aims</h4>Hepatorenal syndrome (HRS) is a disastrous renal complication of advanced liver disease with a poor prognosis. Restoring normal liver function through liver transplantation (LT) is a standardized treatment with favorable short-term survival. However, the long-term renal outcomes in patients with HRS receiving living donor LT (LDLT) are controversial. This study aimed to investigate the prognostic impact of LDLT in patients with HRS.<h4>Methods</h4>We reviewed adult patients who underwent LDLT between July 2008 and September 2017. Recipients were classified into 1) HRS type 1 (HRS1, <i>N</i> = 11), 2) HRS type 2 (HRS2, <i>N</i> = 19), 3) non-HRS recipients with pre-existing chronic kidney disease (CKD, <i>N</i> = 43), and 4) matched normal renal function (<i>N</iFrontiers in surgery1116728https://www.ebi.ac.uk/biostudies/studies/S-EPMC10106629biostudies-literatureLong-term renal outcomes comparison between patients with chronic kidney disease and hepatorenal syndrome after living donor liver transplantation.PMC10106629Chen CLYong CCTseng HYLin YHLin CCLin LMChan YCWang CCfalseLong-term renal outcomes comparison between patients with chronic kidney disease and hepatorenal syndrome after living donor liver transplantation.<h4>Background and aims</h4>Hepatorenal syndrome (HRS) is a disastrous renal complication of advanced liver disease with a poor prognosis. Restoring normal liver function through liver transplantation (LT) is a standardized treatment with favorable short-term survival. However, the long-term renal outcomes in patients with HRS receiving living donor LT (LDLT) are controversial. This study aimed to investigate the prognostic impact of LDLT in patients with HRS.<h4>Methods</h4>We reviewed adult patients who underwent LDLT between July 2008 and September 2017. Recipients were classified into 1) HRS type 1 (HRS1, <i>N</i> = 11), 2) HRS type 2 (HRS2, <i>N</i> = 19), 3) non-HRS recipients with pre-existing chronic kidney disease (CKD, <i>N</i> = 43), and 4) matched normal renal function (<i>N</i2023-01-01T00:00:00Z20232025-04-18T14:52:47.271Z2025-04-07T01:12:08.214ZS-EPMC101066293707786610.3389/fsurg.2023.1116728