biostudies-literatureUnknown11Mouselimis DIn this clinical vignette, we present the case of an 83-year-old female patient with acute limb ischemia, resulting from a large (1.8 × 2.8 cm) mobile thrombus in the descending aorta. The peripheral obstruction was treated with mechanical thrombectomy, whereas the intra-aortic thrombus was treated conservatively with clopidogrel and fondaparinux. (<b>Level of Difficulty: Beginner.</b>).JACC. Case reports101770https://www.ebi.ac.uk/biostudies/studies/S-EPMC10107008biostudies-literatureSuccessful Conservative Treatment of Mobile Aortic Thrombus Causing Acute Limb Ischemia.PMC10107008Donas KPMouselimis DGiesen AKorosoglou GfalseSuccessful Conservative Treatment of Mobile Aortic Thrombus Causing Acute Limb Ischemia.In this clinical vignette, we present the case of an 83-year-old female patient with acute limb ischemia, resulting from a large (1.8 × 2.8 cm) mobile thrombus in the descending aorta. The peripheral obstruction was treated with mechanical thrombectomy, whereas the intra-aortic thrombus was treated conservatively with clopidogrel and fondaparinux. (<b>Level of Difficulty: Beginner.</b>).2023-01-01T00:00:00Z2023 Apr2025-04-18T14:52:13.739Z2025-04-07T01:10:10.727ZS-EPMC101070083707744010.1016/j.jaccas.2023.101770