{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Parr EB"],"funding":["European Society for Clinical Nutrition and Metabolism"],"pagination":["116-126"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10107304"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["31 Suppl 1"],"pubmed_abstract":["<h4>Objective</h4>This study aimed to assess the impact of time-restricted eating (TRE) on integrated skeletal muscle myofibrillar protein synthesis (MyoPS) rates in males with overweight/obesity.<h4>Methods</h4>A total of 18 healthy males (age 46 ±  5 years; BMI: 30 ± 2 kg/m<sup>2</sup> ) completed this exploratory, parallel, randomized dietary intervention after a 3-day lead-in diet. Participants then consumed an isoenergetic diet (protein: ~1.0 g/kg body mass per day) following either TRE (10:00 a.m. to 6:00 p.m.) or an extended eating control (CON; 8:00 a.m. to 8:00 p.m.) protocol for 10 days. Integrated MyoPS rates were measured using deuterated water administration with repeated saliva, blood, and muscle sampling. Secondary measures included continuous glucose monitoring and body com"],"journal":["Obesity (Silver Spring, Md.)"],"pubmed_title":["Eight-hour time-restricted eating does not lower daily myofibrillar protein synthesis rates: A randomized control trial."],"pmcid":["PMC10107304"],"funding_grant_id":["Early Career Fellowship (to IWKK)"],"pubmed_authors":["Radford BE","Hall RC","Goessens JPB","Wheeler MJ","Senden JM","Kouw IWK","Hawley JA","Parr EB","van Loon LJC"],"additional_accession":[]},"is_claimable":false,"name":"Eight-hour time-restricted eating does not lower daily myofibrillar protein synthesis rates: A randomized control trial.","description":"<h4>Objective</h4>This study aimed to assess the impact of time-restricted eating (TRE) on integrated skeletal muscle myofibrillar protein synthesis (MyoPS) rates in males with overweight/obesity.<h4>Methods</h4>A total of 18 healthy males (age 46 ±  5 years; BMI: 30 ± 2 kg/m<sup>2</sup> ) completed this exploratory, parallel, randomized dietary intervention after a 3-day lead-in diet. Participants then consumed an isoenergetic diet (protein: ~1.0 g/kg body mass per day) following either TRE (10:00 a.m. to 6:00 p.m.) or an extended eating control (CON; 8:00 a.m. to 8:00 p.m.) protocol for 10 days. Integrated MyoPS rates were measured using deuterated water administration with repeated saliva, blood, and muscle sampling. Secondary measures included continuous glucose monitoring and body com","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-06T11:23:42.74Z","creation":"2025-04-06T11:23:42.74Z"},"accession":"S-EPMC10107304","cross_references":{"pubmed":["36546330"],"doi":["10.1002/oby.23637"]}}