{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rodriguez-Calvo J"],"funding":["Instituto de Salud Carlos III"],"pagination":["181-190"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10107431"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["61(2)"],"pubmed_abstract":["<h4>Objective</h4>To analyze the ability to predict perinatal survival and severe neonatal morbidity of cases with early-onset fetal growth restriction (eoFGR) using maternal variables, ultrasound parameters and angiogenic markers at the time of diagnosis.<h4>Methods</h4>This was a prospective observational study in a cohort of singleton pregnancies with a diagnosis of eoFGR (< 32 weeks of gestation). At diagnosis of eoFGR, complete assessment was performed, including ultrasound examination (anatomy, biometry and Doppler assessment) and maternal serum measurement of the angiogenic biomarkers, soluble fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF). Logistic regression models for the prediction of perinatal survival (in cases diagnosed at < 28 weeks) and severe neonat"],"journal":["Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology"],"pubmed_title":["Prediction of perinatal survival in early-onset fetal growth restriction: role of placental growth factor."],"pmcid":["PMC10107431"],"funding_grant_id":["PI13/02405"],"pubmed_authors":["Herraiz I","Galindo A","Quezada MS","Villalain C","Gomez-Arriaga PI","Rodriguez-Calvo J"],"additional_accession":[]},"is_claimable":false,"name":"Prediction of perinatal survival in early-onset fetal growth restriction: role of placental growth factor.","description":"<h4>Objective</h4>To analyze the ability to predict perinatal survival and severe neonatal morbidity of cases with early-onset fetal growth restriction (eoFGR) using maternal variables, ultrasound parameters and angiogenic markers at the time of diagnosis.<h4>Methods</h4>This was a prospective observational study in a cohort of singleton pregnancies with a diagnosis of eoFGR (< 32 weeks of gestation). At diagnosis of eoFGR, complete assessment was performed, including ultrasound examination (anatomy, biometry and Doppler assessment) and maternal serum measurement of the angiogenic biomarkers, soluble fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF). Logistic regression models for the prediction of perinatal survival (in cases diagnosed at < 28 weeks) and severe neonat","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Feb","modification":"2025-04-27T02:36:42.461Z","creation":"2025-04-06T18:38:01.727Z"},"accession":"S-EPMC10107431","cross_references":{"pubmed":["36370447"],"doi":["10.1002/uog.26116"]}}