biostudies-literatureUnknown43(2)Lind LAkademiska Sjukhuset<h4>Objective</h4>Maximal oxygen consumption at an exercise test (VO₂ -max) is a commonly used marker of physical fitness. In the present study, we aimed to find independent clinical predictors of VO₂ -max by use of multiple measurements of cardiac, respiratory and vascular variables collected while resting.<h4>Methods</h4>In the Prospective study of Obesity, Energy and Metabolism (POEM), 420 subjects aged 50 years were investigated regarding endothelial function, arterial compliance, heart rate variability, arterial blood flow and atherosclerosis, left ventricular structure and function, lung function, multiple blood pressure measurements, lifestyle habits, body composition and in addition a maximal bicycle exercise test with gas exchange (VO₂ and VCO<sub>Clinical physiology and functional imaging120-127https://www.ebi.ac.uk/biostudies/studies/S-EPMC10108008biostudies-literatureDetailed investigation of multiple resting cardiovascular parameters in relation to physical fitness.PMC10108008Lind LMichaelsson KfalseDetailed investigation of multiple resting cardiovascular parameters in relation to physical fitness.<h4>Objective</h4>Maximal oxygen consumption at an exercise test (VO₂ -max) is a commonly used marker of physical fitness. In the present study, we aimed to find independent clinical predictors of VO₂ -max by use of multiple measurements of cardiac, respiratory and vascular variables collected while resting.<h4>Methods</h4>In the Prospective study of Obesity, Energy and Metabolism (POEM), 420 subjects aged 50 years were investigated regarding endothelial function, arterial compliance, heart rate variability, arterial blood flow and atherosclerosis, left ventricular structure and function, lung function, multiple blood pressure measurements, lifestyle habits, body composition and in addition a maximal bicycle exercise test with gas exchange (VO₂ and VCO<sub>2023-01-01T00:00:00Z2023 Mar2025-04-04T23:00:43.028Z2025-04-04T23:00:43.028ZS-EPMC101080083640889610.1111/cpf.12800