biostudies-literatureUnknown67(2)Ellekjaer KLRigshospitaletGrosserer Jakob Ehrenreich og Hustru Grete Ehrenreichs FondThe Danish Society of Anesthesiology and Intensive Care Medicine (DASAIM)DASAIM<h4>Background</h4>Intravenous (IV) fluid therapy is a ubiquitous intervention in daily clinical practice. However, nationwide detailed hospital- and departmental-level information on IV fluid use is limited. Hence, we aimed to describe the current issuing of isotonic crystalloid solutions across Danish public hospitals.<h4>Methods</h4>We conducted a nationwide, retrospective observational study describing the issuing of isotonic crystalloid solutions for IV administration, including 0.9% saline, acetate- and lactate-buffered crystalloid solutions. We assessed fluid issuing at national-, regional-, hospital- and departmental-level from 1 January 2021 to 31 December 2021. We obtained sales figures from the Danish Regional Hospital Pharmacies. Regional characteristics were acquired from the Acta anaesthesiologica Scandinavica177-184https://www.ebi.ac.uk/biostudies/studies/S-EPMC10108167biostudies-literatureIssuing of isotonic crystalloid solutions to Danish public hospitals in 2021-A retrospective nationwide observational study.PMC10108167Ellekjaer KLPerner AMoller MHBruun Svan KfalseIssuing of isotonic crystalloid solutions to Danish public hospitals in 2021-A retrospective nationwide observational study.<h4>Background</h4>Intravenous (IV) fluid therapy is a ubiquitous intervention in daily clinical practice. However, nationwide detailed hospital- and departmental-level information on IV fluid use is limited. Hence, we aimed to describe the current issuing of isotonic crystalloid solutions across Danish public hospitals.<h4>Methods</h4>We conducted a nationwide, retrospective observational study describing the issuing of isotonic crystalloid solutions for IV administration, including 0.9% saline, acetate- and lactate-buffered crystalloid solutions. We assessed fluid issuing at national-, regional-, hospital- and departmental-level from 1 January 2021 to 31 December 2021. We obtained sales figures from the Danish Regional Hospital Pharmacies. Regional characteristics were acquired from the 2023-01-01T00:00:00Z2023 Feb2025-07-10T03:08:20.252Z2025-04-06T11:20:35.491ZS-EPMC101081673643748510.1111/aas.14176