biostudies-literatureUnknown61(2)Familiari A<h4>Objective</h4>To evaluate the role of antenatal administration of corticosteroids for fetal lung maturation on the short-term perinatal outcome of pregnancy complicated by late fetal growth restriction (FGR).<h4>Methods</h4>This cohort study was a secondary analysis of a multicenter prospective observational study, the TRUFFLE-2 feasibility study, conducted between 2017 and 2018 in 33 European perinatal centers. The study included women with a singleton pregnancy from 32 + 0 to 36 + 6 weeks of gestation with a fetus considered at risk for FGR, defined as estimated fetal weight (EFW) and/or fetal abdominal circumference < 10^th percentile, or umbilicocerebral ratio (UCR) ≥ 95^th percentile or a drop of more than 40 percentile points in abdominal circumference measureUltrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology191-197https://www.ebi.ac.uk/biostudies/studies/S-EPMC10108243biostudies-literatureAntenatal corticosteroids and perinatal outcome in late fetal growth restriction: analysis of prospective cohort.PMC10108243Visser GHAGyselaers WLees CMecacci FKrofta LMaruotti GMNapolitano RGordijn SJTRUFFLE-2 feasibility study investigatorsBrodszki JRaio LBergman ERichter JBreeze ACHecher KKlaritsch PDerks JBGanzevoort WSande RKWee LThornton JWolf HFrusca TLindgren PBerger ACesari EMarlow NEbbing CPrefumo FLobmaier SMBhide ACetin IFamiliari ABilardo CMCalda PMylrea-Foley BStampalija TArabin BFerrazzi EMyklestad KValensise HfalseAntenatal corticosteroids and perinatal outcome in late fetal growth restriction: analysis of prospective cohort.<h4>Objective</h4>To evaluate the role of antenatal administration of corticosteroids for fetal lung maturation on the short-term perinatal outcome of pregnancy complicated by late fetal growth restriction (FGR).<h4>Methods</h4>This cohort study was a secondary analysis of a multicenter prospective observational study, the TRUFFLE-2 feasibility study, conducted between 2017 and 2018 in 33 European perinatal centers. The study included women with a singleton pregnancy from 32 + 0 to 36 + 6 weeks of gestation with a fetus considered at risk for FGR, defined as estimated fetal weight (EFW) and/or fetal abdominal circumference < 10^th percentile, or umbilicocerebral ratio (UCR) ≥ 95^th percentile or a drop of more than 40 percentile points in abdominal circumference measure2023-01-01T00:00:00Z2023 Feb2025-04-06T11:20:31.612Z2025-04-06T11:20:31.612ZS-EPMC101082433641297510.1002/uog.26127