{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Haslinger C"],"funding":["Austrian Science Fund FWF"],"pagination":["459-471"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10113345"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["154(5)"],"pubmed_abstract":["Herein, we present a new route to synthesize poly(2-oxazoline)s (POx) with coumarin moieties as pendant groups that can be crosslinked by irradiation to form hydrogels. The synthesis of a novel coumarin-containing 2-oxazoline monomer, 2-[(4-methyl-7-coumarinyloxy)methyl]oxazoline is described in four steps and further its subsequent homo- and copolymerization with 2-ethyl-2-oxazoline (EtOx) via cationic ring-opening polymerization (CROP). The received polymers with different coumarin content (8, 4 and 2 mol%) were compared with a known copolymer synthesized via postpolymerization modification of partially hydrolyzed poly(2-ethyl-2-oxazoline) (PEtOx) with a coumarin derivative. The thermoresponsive behavior of the POx in aqueous solutions was investigated, showing a clear difference in the "],"journal":["Monatshefte fur chemie"],"pubmed_title":["Synthesis of coumarin-containing poly(2-oxazoline)s and light-induced crosslinking for hydrogel formation."],"pmcid":["PMC10113345"],"funding_grant_id":["M 2805"],"pubmed_authors":["Haslinger C","Zahoranova A","Baudis S"],"additional_accession":[]},"is_claimable":false,"name":"Synthesis of coumarin-containing poly(2-oxazoline)s and light-induced crosslinking for hydrogel formation.","description":"Herein, we present a new route to synthesize poly(2-oxazoline)s (POx) with coumarin moieties as pendant groups that can be crosslinked by irradiation to form hydrogels. The synthesis of a novel coumarin-containing 2-oxazoline monomer, 2-[(4-methyl-7-coumarinyloxy)methyl]oxazoline is described in four steps and further its subsequent homo- and copolymerization with 2-ethyl-2-oxazoline (EtOx) via cationic ring-opening polymerization (CROP). The received polymers with different coumarin content (8, 4 and 2 mol%) were compared with a known copolymer synthesized via postpolymerization modification of partially hydrolyzed poly(2-ethyl-2-oxazoline) (PEtOx) with a coumarin derivative. The thermoresponsive behavior of the POx in aqueous solutions was investigated, showing a clear difference in the ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-22T01:38:31.529Z","creation":"2025-04-05T20:05:40.707Z"},"accession":"S-EPMC10113345","cross_references":{"pubmed":["37091355"],"doi":["10.1007/s00706-022-03013-8"]}}