{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Leistner R"],"funding":["Bundesministerium für Bildung und Forschung","Bill and Melinda Gates Foundation","Federal Ministry of Education and Research Berlin Office"],"pagination":["101958"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10113752"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["59"],"pubmed_abstract":["Background
The impact of environmental hygiene on the occurrence of hospital-acquired infections (HAIs) remains a subject of debate. We determined the effect of three different surface-cleaning strategies on the incidence of HAIs.Methods
Between June 2017 and August 2018 we conducted a pragmatic, cluster-randomized controlled crossover trial at 18 non-ICU wards in the university hospital of Berlin, Germany. Surfaces in patient rooms on the study wards were routinely cleaned using one of three agents: Soap-based (reference), disinfectant and probiotic. Each strategy was used on each ward for four consecutive months (4m-4m-4m). There was a one-month wash-in period at the beginning of the study and after each change in strategy. The order of strategies used was randomized for "],"journal":["EClinicalMedicine"],"pubmed_title":["Environmental cleaning to prevent hospital-acquired infections on non-intensive care units: a pragmatic, single-centre, cluster randomized controlled, crossover trial comparing soap-based, disinfection and probiotic cleaning."],"pmcid":["PMC10113752"],"funding_grant_id":["03Z0818C","KARMIN – 03Z0818C","INV-004308"],"pubmed_authors":["Lemke E","Zakonsky G","Leistner R","Brodzinski A","Kohlmorgen B","Schwab F","Gastmeier P"],"additional_accession":[]},"is_claimable":false,"name":"Environmental cleaning to prevent hospital-acquired infections on non-intensive care units: a pragmatic, single-centre, cluster randomized controlled, crossover trial comparing soap-based, disinfection and probiotic cleaning.","description":"Background
The impact of environmental hygiene on the occurrence of hospital-acquired infections (HAIs) remains a subject of debate. We determined the effect of three different surface-cleaning strategies on the incidence of HAIs.Methods
Between June 2017 and August 2018 we conducted a pragmatic, cluster-randomized controlled crossover trial at 18 non-ICU wards in the university hospital of Berlin, Germany. Surfaces in patient rooms on the study wards were routinely cleaned using one of three agents: Soap-based (reference), disinfectant and probiotic. Each strategy was used on each ward for four consecutive months (4m-4m-4m). There was a one-month wash-in period at the beginning of the study and after each change in strategy. The order of strategies used was randomized for ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2026-04-12T19:22:10.573Z","creation":"2025-04-05T20:03:33.632Z"},"accession":"S-EPMC10113752","cross_references":{"pubmed":["37089619"],"doi":["10.1016/j.eclinm.2023.101958"]}}