{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Villacis-Perez E"],"funding":["China Scholarship Council","European Research Council"],"pagination":["863-879"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10130554"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(4)"],"pubmed_abstract":["Pesticide resistance relies on a myriad of mechanisms, ranging from single mutations to a complex and polygenic architecture, and it involves mechanisms such as target-site insensitivity, metabolic detoxification, or a combination of these, with either additive or synergistic effects. Several resistance mechanisms against abamectin, a macrocyclic lactone widely used in crop protection, have been reported in the cosmopolitan pest <i>Tetranychus urticae</i>. However, it has been shown that a single mechanism cannot account for the high levels of abamectin resistance found across different mite populations. Here, we used experimental evolution combined with bulked segregant analyses to map quantitative trait loci (QTL) associated with abamectin resistance in two genetically unrelated populati"],"journal":["Evolutionary applications"],"pubmed_title":["Intraspecific diversity in the mechanisms underlying abamectin resistance in a cosmopolitan pest."],"pmcid":["PMC10130554"],"funding_grant_id":["773902","773902‐SuperPests","772026","772026‐POLYADAPT"],"pubmed_authors":["Xue W","Villacis-Perez E","Dermauw W","Van Leeuwen T","De Beer B","Vandenhole M"],"additional_accession":[]},"is_claimable":false,"name":"Intraspecific diversity in the mechanisms underlying abamectin resistance in a cosmopolitan pest.","description":"Pesticide resistance relies on a myriad of mechanisms, ranging from single mutations to a complex and polygenic architecture, and it involves mechanisms such as target-site insensitivity, metabolic detoxification, or a combination of these, with either additive or synergistic effects. Several resistance mechanisms against abamectin, a macrocyclic lactone widely used in crop protection, have been reported in the cosmopolitan pest <i>Tetranychus urticae</i>. However, it has been shown that a single mechanism cannot account for the high levels of abamectin resistance found across different mite populations. Here, we used experimental evolution combined with bulked segregant analyses to map quantitative trait loci (QTL) associated with abamectin resistance in two genetically unrelated populati","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Apr","modification":"2026-05-28T22:39:54.794Z","creation":"2025-04-04T20:20:43.667Z"},"accession":"S-EPMC10130554","cross_references":{"pubmed":["37124092"],"doi":["10.1111/eva.13542"]}}