biostudies-literatureUnknown23(1)Nakagawara K<h4>Background</h4>Although cases of respiratory bacterial infections associated with coronavirus disease 2019 (COVID-19) have often been reported, their impact on the clinical course remains unclear. Herein, we evaluated and analyzed the complication rates of bacterial infections, causative organisms, patient backgrounds, and clinical outcome in Japanese patients with COVID-19.<h4>Methods</h4>We performed a retrospective cohort study that included inpatients with COVID-19 from multiple centers participating in the Japan COVID-19 Taskforce (April 2020 to May 2021) and obtained demographic, epidemiological, and microbiological results and the clinical course and analyzed the cases of COVID-19 complicated by respiratory bacterial infections.<h4>Results</h4>Of the 1,863 patients with COVID-19BMC pulmonary medicine146https://www.ebi.ac.uk/biostudies/studies/S-EPMC10131342biostudies-literatureImpact of respiratory bacterial infections on mortality in Japanese patients with COVID-19: a retrospective cohort study.PMC10131342Odani TNakamori YKawamura KMutoh YOno THosoda YYoshiyama TTanino YMashimo SWatase MWatanabe HOtsuki RKawana AAsakura TKamata HKumanogoh AKanai TKoike RKita TJapan COVID-19 Task ForceSaito FKimura AAmishima MSano HOgawa SNishi KKimura YLee HSato YNamkoong HKatayama KKimizuka YChubachi SMorita AMasuda MHashimoto SMiyano SAzekawa SIshikura HShoko THashimoto NKuwahara NIshii MOkamoto MTokunaga KKuramochi MAi MChihara YSato TMiyazawa NKono YNagasaki YTakaku YIshii TFukunaga KKusumoto TFujitani SKagaya TOtake SKusaka YAndo AShirai YTakano TOhba TTanaka HKitagawa YFukui MTsuchida TEdahiro RIshiguro THasegawa YAbe SMasaki KKasamatsu YFukushima TTakata TEndo AMori NTani MMurakami KHasegawa NMatsushita YMochimaru TImoto SHagiwara EKataoka KUeda SOgura SKitamura HUeda TFujiwara AHarada NKokutou HOkada YMiyawaki MOno HMuranaka HNakagawara KfalseImpact of respiratory bacterial infections on mortality in Japanese patients with COVID-19: a retrospective cohort study.<h4>Background</h4>Although cases of respiratory bacterial infections associated with coronavirus disease 2019 (COVID-19) have often been reported, their impact on the clinical course remains unclear. Herein, we evaluated and analyzed the complication rates of bacterial infections, causative organisms, patient backgrounds, and clinical outcome in Japanese patients with COVID-19.<h4>Methods</h4>We performed a retrospective cohort study that included inpatients with COVID-19 from multiple centers participating in the Japan COVID-19 Taskforce (April 2020 to May 2021) and obtained demographic, epidemiological, and microbiological results and the clinical course and analyzed the cases of COVID-19 complicated by respiratory bacterial infections.<h4>Results</h4>Of the 1,863 patients with COVID-192023-01-01T00:00:00Z2023 Apr2025-04-22T13:13:26.201Z2025-04-06T00:32:48.74ZS-EPMC101313423710126510.1186/s12890-023-02418-3