{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Xie Q"],"funding":["National Natural Science Foundation of China"],"pagination":["500"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10135650"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(4)"],"pubmed_abstract":["Licha black (LI) pig has the specific characteristics of larger body length and appropriate fat deposition among Chinese indigenous pigs. Body length is one of the external traits that affect production performance, and fat deposition influences meat quality. However, the genetic characteristics of LI pigs have not yet been systematically uncovered. Here, the genomic information from 891 individuals of LI pigs, commercial pigs, and other Chinese indigenous pigs was used to analyze the breed characteristics of the LI pig with runs of homozygosity, haplotype, and <i>F<sub>ST</sub></i> selection signatures. The results showed the growth traits-related genes (i.e., <i>NR6A1</i> and <i>PAPPA2</i>) and the fatness traits-related gene (i.e., <i>PIK3C2B</i>) were the promising candidate genes that"],"journal":["Biology"],"pubmed_title":["Integration of Selection Signatures and Protein Interactions Reveals <i>NR6A1</i>, <i>PAPPA2</i>, and <i>PIK3C2B</i> as the Promising Candidate Genes Underlying the Characteristics of Licha Black Pig."],"pmcid":["PMC10135650"],"funding_grant_id":["32272833"],"pubmed_authors":["Pan Y","Wang Q","Zhang Z","Chen Z","Xie Q","Sun J","Li M"],"additional_accession":[]},"is_claimable":false,"name":"Integration of Selection Signatures and Protein Interactions Reveals <i>NR6A1</i>, <i>PAPPA2</i>, and <i>PIK3C2B</i> as the Promising Candidate Genes Underlying the Characteristics of Licha Black Pig.","description":"Licha black (LI) pig has the specific characteristics of larger body length and appropriate fat deposition among Chinese indigenous pigs. Body length is one of the external traits that affect production performance, and fat deposition influences meat quality. However, the genetic characteristics of LI pigs have not yet been systematically uncovered. Here, the genomic information from 891 individuals of LI pigs, commercial pigs, and other Chinese indigenous pigs was used to analyze the breed characteristics of the LI pig with runs of homozygosity, haplotype, and <i>F<sub>ST</sub></i> selection signatures. The results showed the growth traits-related genes (i.e., <i>NR6A1</i> and <i>PAPPA2</i>) and the fatness traits-related gene (i.e., <i>PIK3C2B</i>) were the promising candidate genes that","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Mar","modification":"2025-04-04T11:05:28.111Z","creation":"2025-04-04T11:05:28.111Z"},"accession":"S-EPMC10135650","cross_references":{"pubmed":["37106701"],"doi":["10.3390/biology12040500"]}}