{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wiglusz K"],"funding":["Ministry of Science and Higher Education","National Science Center"],"pagination":["271"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10137577"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(4)"],"pubmed_abstract":["The aim of this work was to prepare a new hydrogel based on nanohydroxyapatite (nFAP, 10% <i>w/w</i>) and fluorides (4% <i>w/w</i>), both of which are used as sources of fluoride ions in the treatment of dentin hypersensitivity, and to characterize its physicochemical properties. The release of fluoride ions from 3 gels (G-F, G-F-nFAP, and G-nFAP gel) was controlled in Fusayama-Meyer artificial saliva at pH 4.5, 6.6, and 8.0. The properties of the formulations were determined by an analysis of viscosity, a shear rate test, a swelling study, and gel aging. Various methods, i.e., FT-IR spectroscopy, UV-VIS spectroscopy, and thermogravimetric, electrochemical, and rheological analysis, were used for the experiment. The profiles of fluoride release indicate that the amount of fluoride ions rel"],"journal":["Gels (Basel, Switzerland)"],"pubmed_title":["Nanofluorapatite Hydrogels in the Treatment of Dentin Hypersensitivity: A Study of Physiochemical Properties and Fluoride Release."],"pmcid":["PMC10137577"],"funding_grant_id":["MINI.B180.22.007","SUBZ.D290.23.031","UMO-2021/43/B/ST5/02960"],"pubmed_authors":["Wiglusz K","Dobrzynski M","Wiglusz RJ","Gutbier M"],"additional_accession":[]},"is_claimable":false,"name":"Nanofluorapatite Hydrogels in the Treatment of Dentin Hypersensitivity: A Study of Physiochemical Properties and Fluoride Release.","description":"The aim of this work was to prepare a new hydrogel based on nanohydroxyapatite (nFAP, 10% <i>w/w</i>) and fluorides (4% <i>w/w</i>), both of which are used as sources of fluoride ions in the treatment of dentin hypersensitivity, and to characterize its physicochemical properties. The release of fluoride ions from 3 gels (G-F, G-F-nFAP, and G-nFAP gel) was controlled in Fusayama-Meyer artificial saliva at pH 4.5, 6.6, and 8.0. The properties of the formulations were determined by an analysis of viscosity, a shear rate test, a swelling study, and gel aging. Various methods, i.e., FT-IR spectroscopy, UV-VIS spectroscopy, and thermogravimetric, electrochemical, and rheological analysis, were used for the experiment. The profiles of fluoride release indicate that the amount of fluoride ions rel","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Mar","modification":"2025-04-04T11:05:12.479Z","creation":"2025-04-04T11:05:12.479Z"},"accession":"S-EPMC10137577","cross_references":{"pubmed":["37102883"],"doi":["10.3390/gels9040271"]}}