biostudies-literaturePlaza-Diaz JAlter Farmacia S. AAlter Farmacia S A7392https://www.ebi.ac.uk/biostudies/studies/S-EPMC10139017biostudies-literatureUnknown24(8)The World Health Organization recommends exclusive breastfeeding on demand until at least the sixth month of life. Breast milk or infant formula is the infant's primary food source until the age of one year, followed by the gradual introduction of other foods. During weaning, the intestinal microbiota evolves to a profile close to that of the adult, and its disruption can result in an increased incidence of acute infectious diseases. We aimed to determine whether a novel starting formula (INN) provides gut microbiota compositions more similar to those of breastfed (BF) infants from 6 to 12 months of age compared to a standard formula (STD). This study included 210 infants (70 per group) who completed the intervention until they reached the age of 12 months. In the intervention period, infaInternational journal of molecular sciencesInnova 2020: A Follow-Up Study of the Fecal Microbiota of Infants Using a Novel Infant Formula between 6 Months and 12 Months of Age.PMC10139017INNOVA2020Ruiz-Ojeda FJMartin-Masot RAlvarez BTortajada MPlaza-Diaz JGil AMartinez-Blanch JFMorales JRamon DSilva ACliment EChenoll EEnrique MfalseInnova 2020: A Follow-Up Study of the Fecal Microbiota of Infants Using a Novel Infant Formula between 6 Months and 12 Months of Age.The World Health Organization recommends exclusive breastfeeding on demand until at least the sixth month of life. Breast milk or infant formula is the infant's primary food source until the age of one year, followed by the gradual introduction of other foods. During weaning, the intestinal microbiota evolves to a profile close to that of the adult, and its disruption can result in an increased incidence of acute infectious diseases. We aimed to determine whether a novel starting formula (INN) provides gut microbiota compositions more similar to those of breastfed (BF) infants from 6 to 12 months of age compared to a standard formula (STD). This study included 210 infants (70 per group) who completed the intervention until they reached the age of 12 months. In the intervention period, infa2023-01-01T00:00:00Z2023 Apr2026-04-08T13:16:02.55Z2024-11-20T12:12:19.781ZS-EPMC101390173710855510.3390/ijms24087392