biostudies-literatureTerekhov MBundesministerium für Bildung und ForschungDeutsche ForschungsgemeinschaftUniversitätsklinikum Würzburg279-293https://www.ebi.ac.uk/biostudies/studies/S-EPMC10140105biostudies-literatureUnknown36(2)<h4>Introduction</h4>MRI of excised hearts at ultra-high field strengths ([Formula: see text]≥7 T) can provide high-resolution, high-fidelity ground truth data for biomedical studies, imaging science, and artificial intelligence. In this study, we demonstrate the capabilities of a custom-built, multiple-element transceiver array customized for high-resolution imaging of excised hearts.<h4>Method</h4>A dedicated 16-element transceiver loop array was implemented for operation in parallel transmit (pTx) mode (8Tx/16Rx) of a clinical whole-body 7 T MRI system. The initial adjustment of the array was performed using full-wave 3D-electromagnetic simulation with subsequent final fine-tuning on the bench.<h4>Results</h4>We report the results of testing the implemented array in tissue-mimicking liquid phantoms and excised porcine hearts. The array demonstrated high efficiency of parallel transmits characteristics enabling efficient pTX-based B₁⁺-shimming.<h4>Conclusion</h4>The receive sensitivity and parallel imaging capability of the dedicated coil were superior to that of a commercial 1Tx/32Rx head coil in both SNR and T₂*-mapping. The array was successfully tested to acquire ultra-high-resolution (0.1 × 0.1 × 0.8 mm voxel) images of post-infarction scar tissue. High-resolution (isotropic 1.6 mm³ voxel) diffusion tensor imaging-based tractography provided high-resolution information about normal myocardial fiber orientation.Magma (New York, N.Y.)High-resolution imaging of the excised porcine heart at a whole-body 7 T MRI system using an 8Tx/16Rx pTx coil.PMC1014010501EO100401EO1504453989101Hofmann UElabyad IALohr DSchreiber LMTerekhov MfalseHigh-resolution imaging of the excised porcine heart at a whole-body 7 T MRI system using an 8Tx/16Rx pTx coil.<h4>Introduction</h4>MRI of excised hearts at ultra-high field strengths ([Formula: see text]≥7 T) can provide high-resolution, high-fidelity ground truth data for biomedical studies, imaging science, and artificial intelligence. In this study, we demonstrate the capabilities of a custom-built, multiple-element transceiver array customized for high-resolution imaging of excised hearts.<h4>Method</h4>A dedicated 16-element transceiver loop array was implemented for operation in parallel transmit (pTx) mode (8Tx/16Rx) of a clinical whole-body 7 T MRI system. The initial adjustment of the array was performed using full-wave 3D-electromagnetic simulation with subsequent final fine-tuning on the bench.<h4>Results</h4>We report the results of testing the implemented array in tissue-mimicking liquid phantoms and excised porcine hearts. The array demonstrated high efficiency of parallel transmits characteristics enabling efficient pTX-based B₁⁺-shimming.<h4>Conclusion</h4>The receive sensitivity and parallel imaging capability of the dedicated coil were superior to that of a commercial 1Tx/32Rx head coil in both SNR and T₂*-mapping. The array was successfully tested to acquire ultra-high-resolution (0.1 × 0.1 × 0.8 mm voxel) images of post-infarction scar tissue. High-resolution (isotropic 1.6 mm³ voxel) diffusion tensor imaging-based tractography provided high-resolution information about normal myocardial fiber orientation.2023-01-01T00:00:00Z2023 Apr2024-10-18T18:34:48.592Z2024-10-18T18:34:48.592ZS-EPMC101401053702711910.1007/s10334-023-01077-z