{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15(4)"],"submitter":["Nguyen NN"],"pubmed_abstract":["Since the discovery of SARS-CoV-2, changes in genotype and reinfection with different variants have been observed in COVID-19-recovered patients, raising questions around the clinical pattern and severity of primary infection and reinfection. In this systematic review, we summarize the results of 23 studies addressing SARS-CoV-2 reinfections. A total of 23,231 reinfected patients were included, with pooled estimated reinfection rates ranging from 0.1 to 6.8%. Reinfections were more prevalent during the Omicron variant period. The mean age of reinfected patients was 38.0 ± 6. years and females were predominant among reinfected patients (M/F = 0.8). The most common symptoms during the first and second infection were fever (41.1%), cough (35.7% and 44.6%), myalgia (34.5% and 33.3%), fatigue ("],"journal":["Viruses"],"pagination":["967"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10145185"],"repository":["biostudies-literature"],"pubmed_title":["SARS-CoV-2 Reinfection and Severity of the Disease: A Systematic Review and Meta-Analysis."],"pmcid":["PMC10145185"],"pubmed_authors":["Hoang VT","Million M","Nguyen NN","Gautret P","Nguyen YN"],"additional_accession":[]},"is_claimable":false,"name":"SARS-CoV-2 Reinfection and Severity of the Disease: A Systematic Review and Meta-Analysis.","description":"Since the discovery of SARS-CoV-2, changes in genotype and reinfection with different variants have been observed in COVID-19-recovered patients, raising questions around the clinical pattern and severity of primary infection and reinfection. In this systematic review, we summarize the results of 23 studies addressing SARS-CoV-2 reinfections. A total of 23,231 reinfected patients were included, with pooled estimated reinfection rates ranging from 0.1 to 6.8%. Reinfections were more prevalent during the Omicron variant period. The mean age of reinfected patients was 38.0 ± 6. years and females were predominant among reinfected patients (M/F = 0.8). The most common symptoms during the first and second infection were fever (41.1%), cough (35.7% and 44.6%), myalgia (34.5% and 33.3%), fatigue (","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Apr","modification":"2025-04-21T17:27:16.273Z","creation":"2025-04-05T16:40:52.443Z"},"accession":"S-EPMC10145185","cross_references":{"pubmed":["37112949"],"doi":["10.3390/v15040967"]}}