biostudies-literatureUnknown13(4)Rosso C<h4>Background</h4>Nasal cytology at birth and in the pediatric age is barely investigated regarding its association with the onset of common pediatric diseases.<h4>Methods</h4>We enrolled 241 newborns within their first 24 h of life, studying their nasal cellular composition and repeating this at 1 and 3 years of life. We collected anamneses of perinatal factors and external factors (parental smoking, passive smoking, breastfeeding), and the prevalence of otitis, rhinosinusitis, bronchitis, asthma, and allergy at all timepoints.<h4>Results</h4>204 children completed the study. At birth, there was a prevalence of ciliated cells and rare neutrophils. At 1 and 3 years, ciliated cells started reducing in favor of muciparous cells and neutrophils. We found that caesarian delivery and nasogastrJournal of personalized medicine687https://www.ebi.ac.uk/biostudies/studies/S-EPMC10146100biostudies-literatureNasal Cytology on 241 Children: From Birth to the First 3 Years of Life and Association with Common Airways Diseases.PMC10146100Fuccillo EVerduci EFerraroni MPipolo CRosso CSaibene AMMagnani MDe Corso ETurati FFelisati GBanderali GTavilla MCfalseNasal Cytology on 241 Children: From Birth to the First 3 Years of Life and Association with Common Airways Diseases.<h4>Background</h4>Nasal cytology at birth and in the pediatric age is barely investigated regarding its association with the onset of common pediatric diseases.<h4>Methods</h4>We enrolled 241 newborns within their first 24 h of life, studying their nasal cellular composition and repeating this at 1 and 3 years of life. We collected anamneses of perinatal factors and external factors (parental smoking, passive smoking, breastfeeding), and the prevalence of otitis, rhinosinusitis, bronchitis, asthma, and allergy at all timepoints.<h4>Results</h4>204 children completed the study. At birth, there was a prevalence of ciliated cells and rare neutrophils. At 1 and 3 years, ciliated cells started reducing in favor of muciparous cells and neutrophils. We found that caesarian delivery and nasogastr2023-01-01T00:00:00Z2023 Apr2025-04-21T17:30:53.662Z2025-04-05T16:40:05.898ZS-EPMC101461003710907310.3390/jpm13040687