{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(1)"],"submitter":["Flaus A"],"pubmed_abstract":["<h4>Background</h4>To show the equivalence between the specific binding ratios (SBR) of visually normal <sup>123</sup>I-FP-CIT SPECT scans from patients to those from healthy volunteers (Hv) or patients without dopaminergic degeneration to allow their use as a reference database.<h4>Methods</h4>The SBR values of visually normal SPECT scans from 3 groups were studied: (1) suspected Parkinsonism and no diagnostic follow-up (ScanOnlyDB: n = 764, NM/CT 670 CZT, GE Healthcare), (2) no degenerative dopaminergic pathology after a 5-year follow-up (NoDG5YearsDB: n = 237, Symbia T2, Siemens Medical Solutions), and 3) Hv (HvDB: n = 118, commercial GE database). A general linear model (GLM) was constructed with caudate, putamen, and striatum SBR as the dependent variables, and age and gender as the i"],"journal":["EJNMMI research"],"pagination":["37"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10147889"],"repository":["biostudies-literature"],"pubmed_title":["Semi-quantitative analysis of visually normal <sup>123</sup>I-FP-CIT across three large databases revealed no difference between control and patients."],"pmcid":["PMC10147889"],"pubmed_authors":["Philippe R","Scheiber C","Janier M","Flaus A","Thobois S"],"additional_accession":[]},"is_claimable":false,"name":"Semi-quantitative analysis of visually normal <sup>123</sup>I-FP-CIT across three large databases revealed no difference between control and patients.","description":"<h4>Background</h4>To show the equivalence between the specific binding ratios (SBR) of visually normal <sup>123</sup>I-FP-CIT SPECT scans from patients to those from healthy volunteers (Hv) or patients without dopaminergic degeneration to allow their use as a reference database.<h4>Methods</h4>The SBR values of visually normal SPECT scans from 3 groups were studied: (1) suspected Parkinsonism and no diagnostic follow-up (ScanOnlyDB: n = 764, NM/CT 670 CZT, GE Healthcare), (2) no degenerative dopaminergic pathology after a 5-year follow-up (NoDG5YearsDB: n = 237, Symbia T2, Siemens Medical Solutions), and 3) Hv (HvDB: n = 118, commercial GE database). A general linear model (GLM) was constructed with caudate, putamen, and striatum SBR as the dependent variables, and age and gender as the i","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Apr","modification":"2025-05-29T20:47:48.1Z","creation":"2024-11-07T08:48:48.252Z"},"accession":"S-EPMC10147889","cross_references":{"pubmed":["37117951"],"doi":["10.1186/s13550-023-00983-6"]}}