{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Aqil A"],"funding":["Division of Environmental Biology","National Geographic Society","Division of Earth Sciences","National Science Foundation"],"pagination":["106581"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10149335"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["26(5)"],"pubmed_abstract":["Many specifics of the population histories of the Indigenous peoples of North America remain contentious owing to a dearth of physical evidence. Only few ancient human genomes have been recovered from the Pacific Northwest Coast, a region increasingly supported as a coastal migration route for the initial peopling of the Americas. Here, we report paleogenomic data from the remains of a ∼3,000-year-old female individual from Southeast Alaska, named <i>Tatóok yík yées sháawat</i> (<i>TYYS</i>). Our results demonstrate at least 3,000 years of matrilineal genetic continuity in Southeast Alaska, and that <i>TYYS</i> is most closely related to ancient and present-day northern Pacific Northwest Coast Indigenous Americans. We find no evidence of Paleo-Inuit (represented by <i>Saqqaq</i>) ancestry in present-day or ancient Pacific Northwest peoples. Instead, our analyses suggest the <i>Saqqaq</i> genome harbors Northern Native American ancestry. This study sheds further light on the human population history of the northern Pacific Northwest Coast."],"journal":["iScience"],"pubmed_title":["A paleogenome from a Holocene individual supports genetic continuity in Southeast Alaska."],"pmcid":["PMC10149335"],"funding_grant_id":["6212-98","0208247","1556565","9870343","1854550"],"pubmed_authors":["Aqil A","Heaton TT","Malhi RS","Gill S","Gokcumen O","Smith JL","Reese EA","Lindqvist C"],"additional_accession":[]},"is_claimable":false,"name":"A paleogenome from a Holocene individual supports genetic continuity in Southeast Alaska.","description":"Many specifics of the population histories of the Indigenous peoples of North America remain contentious owing to a dearth of physical evidence. Only few ancient human genomes have been recovered from the Pacific Northwest Coast, a region increasingly supported as a coastal migration route for the initial peopling of the Americas. Here, we report paleogenomic data from the remains of a ∼3,000-year-old female individual from Southeast Alaska, named <i>Tatóok yík yées sháawat</i> (<i>TYYS</i>). Our results demonstrate at least 3,000 years of matrilineal genetic continuity in Southeast Alaska, and that <i>TYYS</i> is most closely related to ancient and present-day northern Pacific Northwest Coast Indigenous Americans. We find no evidence of Paleo-Inuit (represented by <i>Saqqaq</i>) ancestry in present-day or ancient Pacific Northwest peoples. Instead, our analyses suggest the <i>Saqqaq</i> genome harbors Northern Native American ancestry. This study sheds further light on the human population history of the northern Pacific Northwest Coast.","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2024-10-19T13:43:31.849Z","creation":"2024-10-19T13:43:31.849Z"},"accession":"S-EPMC10149335","cross_references":{"pubmed":["37138779"],"doi":["10.1016/j.isci.2023.106581"]}}