biostudies-literatureUnknown21(1)Yang Q<h4>Background</h4>It remains unknown whether anticoagulation for persistent left ventricular (LV) thrombus should be continued indefinitely. Identifying patients with a high risk of thrombus unresolved may be helpful to determine the optimum anticoagulation duration. This study aimed to develop a prediction model to forecast thrombus persistence or recurrence in patients with LV thrombus.<h4>Methods</h4>We enrolled patients prospectively from 2020 to 2022 and retrospectively from 2013 to 2019 at the National Center of Cardiovascular Diseases of China. The two cohorts were then combined to derive predictive models of thrombus persistence/recurrence. The primary study comprised patients who received systemic oral anticoagulants and had imaging records available at the end of a 3-month folloThrombosis journal50https://www.ebi.ac.uk/biostudies/studies/S-EPMC10150477biostudies-literatureA prediction model for left ventricular thrombus persistence/recurrence: based on a prospective study and a retrospective study.PMC10150477Yu LYang YZhu JWang CLiang YYang QQuan XfalseA prediction model for left ventricular thrombus persistence/recurrence: based on a prospective study and a retrospective study.<h4>Background</h4>It remains unknown whether anticoagulation for persistent left ventricular (LV) thrombus should be continued indefinitely. Identifying patients with a high risk of thrombus unresolved may be helpful to determine the optimum anticoagulation duration. This study aimed to develop a prediction model to forecast thrombus persistence or recurrence in patients with LV thrombus.<h4>Methods</h4>We enrolled patients prospectively from 2020 to 2022 and retrospectively from 2013 to 2019 at the National Center of Cardiovascular Diseases of China. The two cohorts were then combined to derive predictive models of thrombus persistence/recurrence. The primary study comprised patients who received systemic oral anticoagulants and had imaging records available at the end of a 3-month follo2023-01-01T00:00:00Z2023 May2026-07-14T21:12:25.762Z2024-10-19T13:43:10.701ZS-EPMC101504773712202810.1186/s12959-023-00488-1