biostudies-literatureUnknown2023Zhang QHypochlorite (ClO^-) has received extensive attention owing to its significant roles in the immune defense and pathogenesis of numerous diseases. However, excessive or misplaced production of ClO^- may pose certain diseases. Thus, to determine its biological functions in depth, ClO^- should be tested in biosystems. In this study, a facile, one-pot synthesis of nitrogen-fluorine-doped carbon quantum dots (N, F-CDs) was developed using ammonium citrate tribasic, L-alanine, and ammonium fluoride as raw materials under hydrothermal conditions. The prepared N, F-CDs demonstrate not only strong blue fluorescence emission with a high fluorescence quantum yield (26.3%) but also a small particle size of approximately 2.9 nm, as well as excellent water solubility and biJournal of analytical methods in chemistry7515979https://www.ebi.ac.uk/biostudies/studies/S-EPMC10154095biostudies-literaturePreparation of One-Emission Nitrogen-Fluorine-Doped Carbon Quantum Dots and Their Applications in Environmental Water Samples and Living Cells for ClO^- Detection and Imaging.PMC10154095Tian FLong XDu HLiu SZhang QXie SWu YfalsePreparation of One-Emission Nitrogen-Fluorine-Doped Carbon Quantum Dots and Their Applications in Environmental Water Samples and Living Cells for ClO^- Detection and Imaging.Hypochlorite (ClO^-) has received extensive attention owing to its significant roles in the immune defense and pathogenesis of numerous diseases. However, excessive or misplaced production of ClO^- may pose certain diseases. Thus, to determine its biological functions in depth, ClO^- should be tested in biosystems. In this study, a facile, one-pot synthesis of nitrogen-fluorine-doped carbon quantum dots (N, F-CDs) was developed using ammonium citrate tribasic, L-alanine, and ammonium fluoride as raw materials under hydrothermal conditions. The prepared N, F-CDs demonstrate not only strong blue fluorescence emission with a high fluorescence quantum yield (26.3%) but also a small particle size of approximately 2.9 nm, as well as excellent water solubility and bi2023-01-01T00:00:00Z20232025-04-27T03:22:03.373Z2025-04-06T18:47:12.541ZS-EPMC101540953714417410.1155/2023/7515979