{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["39(4)"],"submitter":["Slot EMH"],"funding":["Polyganics B.V."],"pubmed_abstract":["<h4>Purpose</h4>This study aimed to establish the incidence of CSF leakage in children and associated complications after intradural spinal surgery in three tertiary neurosurgical referral centers and to describe the treatment strategies applied.<h4>Methods</h4>Patients of 18 years or younger who underwent intradural spinal surgery between 2015 and 2021 in three tertiary neurosurgical referral centers were included. Patients who died or were lost to follow-up within six weeks after surgery were excluded. The primary outcome measure was CSF leakage within six weeks after surgery, defined as leakage of CSF through the skin. Secondary outcome measures included the presence of pseudomeningocele (PMC), meningitis, and surgical site infection (SSI).<h4>Results</h4>We included a total of 75 proce"],"journal":["Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery"],"pagination":["1013-1019"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10160141"],"repository":["biostudies-literature"],"pubmed_title":["Cerebrospinal fluid leakage after intradural spinal surgery in children."],"pmcid":["PMC10160141"],"pubmed_authors":["Slot EMH","van Baarsen KM","Hoving EW","Regli L","Germans MR","van Doormaal TPC","Krayenbuhl N"],"additional_accession":[]},"is_claimable":false,"name":"Cerebrospinal fluid leakage after intradural spinal surgery in children.","description":"<h4>Purpose</h4>This study aimed to establish the incidence of CSF leakage in children and associated complications after intradural spinal surgery in three tertiary neurosurgical referral centers and to describe the treatment strategies applied.<h4>Methods</h4>Patients of 18 years or younger who underwent intradural spinal surgery between 2015 and 2021 in three tertiary neurosurgical referral centers were included. Patients who died or were lost to follow-up within six weeks after surgery were excluded. The primary outcome measure was CSF leakage within six weeks after surgery, defined as leakage of CSF through the skin. Secondary outcome measures included the presence of pseudomeningocele (PMC), meningitis, and surgical site infection (SSI).<h4>Results</h4>We included a total of 75 proce","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Apr","modification":"2025-04-22T08:48:03.733Z","creation":"2025-04-05T22:40:38.958Z"},"accession":"S-EPMC10160141","cross_references":{"pubmed":["36790491"],"doi":["10.1007/s00381-022-05797-w"]}}