biostudies-literatureUnknown14Niu JAs a conspicuous trait, peel color is one of the most important characteristics that affects commodity quality and consumer preferences. The locus Y underlying yellow peel in Cucurbita pepo (zucchini) was first reported in 1922; however, its molecular mechanism is still unknown. In this study, a genetic analysis revealed that yellow peel is controlled by a single dominant genetic factor. Furthermore, Y was mapped in a ~170 kb region on chromosome 10 by bulked segregated analysis (BSA) and fine mapping in F2 and BC1 segregating populations. The candidate region harbors fifteen annotated genes, among which Cp4.1LG10g11560 (CpCHLH) is regarded as a promising candidate gene. CpCHLH encodes a magnesium chelatase H subunit involved Frontiers in plant science1159937https://www.ebi.ac.uk/biostudies/studies/S-EPMC10160447biostudies-literatureFine mapping and identifying candidate gene of Y underlying yellow peel in Cucurbita pepo.PMC10160447Tang ZChen QLu XNiu JLei FLiu QWang XXu XfalseFine mapping and identifying candidate gene of Y underlying yellow peel in Cucurbita pepo.As a conspicuous trait, peel color is one of the most important characteristics that affects commodity quality and consumer preferences. The locus Y underlying yellow peel in Cucurbita pepo (zucchini) was first reported in 1922; however, its molecular mechanism is still unknown. In this study, a genetic analysis revealed that yellow peel is controlled by a single dominant genetic factor. Furthermore, Y was mapped in a ~170 kb region on chromosome 10 by bulked segregated analysis (BSA) and fine mapping in F2 and BC1 segregating populations. The candidate region harbors fifteen annotated genes, among which Cp4.1LG10g11560 (CpCHLH) is regarded as a promising candidate gene. CpCHLH encodes a magnesium chelatase H subunit involved 2023-01-01T00:00:00Z20232025-04-05T16:13:34.948Z2025-04-05T16:13:34.948ZS-EPMC101604473715214810.3389/fpls.2023.1159937