{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gaio V"],"funding":["European Centre for Disease Prevention and Control"],"pagination":["e068996"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10163328"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(5)"],"pubmed_abstract":["<h4>Objectives</h4>Healthcare workers (HCWs) were the first to be prioritised for COVID-19 vaccination. This study aims to estimate the COVID-19 vaccine effectiveness (VE) against SARS-CoV-2 symptomatic infection among HCWs in Portuguese hospitals.<h4>Design</h4>Prospective cohort study.<h4>Setting and participants</h4>We analysed data from HCWs (all professional categories) from three central hospitals: one in the Lisbon and Tagus Valley region and two in the central region of mainland Portugal, between December 2020 and March 2022. VE against symptomatic SARS-CoV-2 infection was estimated as one minus the confounder adjusted HRs by Cox models considering age group, sex, self-reported chronic disease and occupational exposure to patients diagnosed with COVID-19 as adjustment variables.<h4"],"journal":["BMJ open"],"pubmed_title":["COVID-19 vaccine effectiveness among healthcare workers: a hospital-based cohort study."],"pmcid":["PMC10163328"],"funding_grant_id":["ECD.12609","ECD.12175","ECD.11486"],"pubmed_authors":["Pacheco V","Santos AJ","Dias C","Gaio V","Araujo L","Antunes I","Faro Viana J","Paiva A","Antunes Goncalves L","Kislaya I","Amaral P","Silva A","Machado A","Pinto Leite P","Nunes B"],"additional_accession":[]},"is_claimable":false,"name":"COVID-19 vaccine effectiveness among healthcare workers: a hospital-based cohort study.","description":"<h4>Objectives</h4>Healthcare workers (HCWs) were the first to be prioritised for COVID-19 vaccination. This study aims to estimate the COVID-19 vaccine effectiveness (VE) against SARS-CoV-2 symptomatic infection among HCWs in Portuguese hospitals.<h4>Design</h4>Prospective cohort study.<h4>Setting and participants</h4>We analysed data from HCWs (all professional categories) from three central hospitals: one in the Lisbon and Tagus Valley region and two in the central region of mainland Portugal, between December 2020 and March 2022. VE against symptomatic SARS-CoV-2 infection was estimated as one minus the confounder adjusted HRs by Cox models considering age group, sex, self-reported chronic disease and occupational exposure to patients diagnosed with COVID-19 as adjustment variables.<h4","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2025-04-22T00:30:36.01Z","creation":"2025-04-05T19:36:15.512Z"},"accession":"S-EPMC10163328","cross_references":{"pubmed":["37130692"],"doi":["10.1136/bmjopen-2022-068996"]}}