biostudies-literatureSimoes Cunha MFoundation for Science and Technologye068725https://www.ebi.ac.uk/biostudies/studies/S-EPMC10163458biostudies-literatureUnknown13(5)<h4>Objectives</h4>Anxiety and depression are relevant comorbidities in asthma, but, in Portugal and Spain, data on this topic are scarce. We assessed, in patients with asthma, the frequency of anxiety and depression using the Hospital Anxiety and Depression Scale (HADS) and the European Quality of Life Five Dimension Questionnaire (EQ-5D); the level of agreement between these questionnaires, and the factors associated with these symptoms.<h4>Methods</h4>This is a secondary analysis of the INSPIRERS studies. A total of 614 adolescents and adults with persistent asthma (32.6±16.9 years, 64.7% female) were recruited from 30 primary care centres and 32 allergy, pulmonology and paediatric clinics. Demographic and clinical characteristics, HADS and EQ-5D were collected. A score ≥8 on Hospital ABMJ openSymptoms of anxiety and depression in patients with persistent asthma: a cross-sectional analysis of the INSPIRERS studies.PMC10163458PTDC/MEC-OUT/29130/2017Camara RAlves-Correia MCardia FMorais Silva PMarques JVFonseca JAVidal CFerreira-Magalhaes MSantos Nda Silva SFerreira TMPereira AMFerreira RAntolin-Amerigo DGuimaraes CMeireles PMorete APascoa RSimoes Cunha MVieira CVasconcelos MJFernandes SAlmeida RLopes CAguiar MAValentim BMourao ARCarvalho JJacome CCoelho DSRibeiro CReis BBordalo DNunes CLozoya CAlves ACalix MJMonteiro RAmaral RPinto DMonteiro LCepa MMarques MLLoureiro CCTaborda-Barata LSilva EfalseSymptoms of anxiety and depression in patients with persistent asthma: a cross-sectional analysis of the INSPIRERS studies.<h4>Objectives</h4>Anxiety and depression are relevant comorbidities in asthma, but, in Portugal and Spain, data on this topic are scarce. We assessed, in patients with asthma, the frequency of anxiety and depression using the Hospital Anxiety and Depression Scale (HADS) and the European Quality of Life Five Dimension Questionnaire (EQ-5D); the level of agreement between these questionnaires, and the factors associated with these symptoms.<h4>Methods</h4>This is a secondary analysis of the INSPIRERS studies. A total of 614 adolescents and adults with persistent asthma (32.6±16.9 years, 64.7% female) were recruited from 30 primary care centres and 32 allergy, pulmonology and paediatric clinics. Demographic and clinical characteristics, HADS and EQ-5D were collected. A score ≥8 on Hospital A2023-01-01T00:00:00Z2023 May2025-04-18T15:13:38.622Z2025-04-07T01:46:50.667ZS-EPMC101634583714709210.1136/bmjopen-2022-068725