biostudies-literatureSteinbrenner MWellcome Trust319-337https://www.ebi.ac.uk/biostudies/studies/S-EPMC10164016biostudies-literatureUnknown36(3)<h4>Background</h4>EEG-fMRI is a useful additional test to localize the epileptogenic zone (EZ) particularly in MRI negative cases. However subject motion presents a particular challenge owing to its large effects on both MRI and EEG signal. Traditionally it is assumed that prospective motion correction (PMC) of fMRI precludes EEG artifact correction.<h4>Methods</h4>Children undergoing presurgical assessment at Great Ormond Street Hospital were included into the study. PMC of fMRI was done using a commercial system with a Moiré Phase Tracking marker and MR-compatible camera. For retrospective EEG correction both a standard and a motion educated EEG artefact correction (REEGMAS) were compared to each other.<h4>Results</h4>Ten children underwent simultaneous EEG-fMRI. Overall head movement wBrain topographyCamera-based Prospective Motion Correction in Paediatric Epilepsy Patients Enables EEG-fMRI Localization Even in High-motion States.PMC10164016WT 203148/Z/16/ZMaziero DLorio SMcDowell APerani SCenteno MSteinbrenner MMoeller FCarmichael DWfalseCamera-based Prospective Motion Correction in Paediatric Epilepsy Patients Enables EEG-fMRI Localization Even in High-motion States.<h4>Background</h4>EEG-fMRI is a useful additional test to localize the epileptogenic zone (EZ) particularly in MRI negative cases. However subject motion presents a particular challenge owing to its large effects on both MRI and EEG signal. Traditionally it is assumed that prospective motion correction (PMC) of fMRI precludes EEG artifact correction.<h4>Methods</h4>Children undergoing presurgical assessment at Great Ormond Street Hospital were included into the study. PMC of fMRI was done using a commercial system with a Moiré Phase Tracking marker and MR-compatible camera. For retrospective EEG correction both a standard and a motion educated EEG artefact correction (REEGMAS) were compared to each other.<h4>Results</h4>Ten children underwent simultaneous EEG-fMRI. Overall head movement w2023-01-01T00:00:00Z2023 May2025-04-26T17:25:43.8Z2025-04-06T15:28:56.329ZS-EPMC101640163693998710.1007/s10548-023-00945-0