{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sullivan S"],"funding":["NCATS NIH HHS","NICHD NIH HHS","NIA NIH HHS","NIDA NIH HHS","NHLBI NIH HHS","NIMH NIH HHS","NIAMS NIH HHS"],"pagination":["e112-e120"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10164352"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["43(4)"],"pubmed_abstract":["Background
Microvascular measures of vascular dysfunction during acute mental stress may be important determinants of major adverse cardiovascular events (MACE), especially among younger and middle-aged women survivors of an acute myocardial infarction.Methods
In the MIMS2 study (Myocardial Infarction and Mental Stress 2), individuals who had been hospitalized for a myocardial infarction in the past 8 months were prospectively followed for 5 years. MACE was defined as a composite index of cardiovascular death and first/recurring events for nonfatal myocardial infarction and hospitalizations for heart failure. Reactive hyperemia index and flow-mediated dilation were used to measure microvascular and endothelial function, respectively, before and 30 minutes after a public-spe"],"journal":["Arteriosclerosis, thrombosis, and vascular biology"],"pubmed_title":["Sex Differences in Vascular Response to Mental Stress and Adverse Cardiovascular Events Among Patients With Ischemic Heart Disease."],"pmcid":["PMC10164352"],"funding_grant_id":["R01 HL109413","UG3 DA048502","L30 HL148912","UH3 DA048502","R01 MH120262","UL1 TR002378","K12 AR084234","T32 HL007745","T32 HL130025","U54 AG062334","K01 HL149982","K12 HD085850"],"pubmed_authors":["Sullivan S","Young A","Hammadah M","Lewis TT","Hu Y","Bremner JD","Mehta PK","Quyyumi AA","Garcia M","Almuwaqqat Z","Alkhoder A","Shah AJ","Moazzami K","Elon L","Vaccarino V","Lima BB","Jajeh MN"],"additional_accession":[]},"is_claimable":false,"name":"Sex Differences in Vascular Response to Mental Stress and Adverse Cardiovascular Events Among Patients With Ischemic Heart Disease.","description":"Background
Microvascular measures of vascular dysfunction during acute mental stress may be important determinants of major adverse cardiovascular events (MACE), especially among younger and middle-aged women survivors of an acute myocardial infarction.Methods
In the MIMS2 study (Myocardial Infarction and Mental Stress 2), individuals who had been hospitalized for a myocardial infarction in the past 8 months were prospectively followed for 5 years. MACE was defined as a composite index of cardiovascular death and first/recurring events for nonfatal myocardial infarction and hospitalizations for heart failure. Reactive hyperemia index and flow-mediated dilation were used to measure microvascular and endothelial function, respectively, before and 30 minutes after a public-spe","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Apr","modification":"2025-04-04T20:15:42.548Z","creation":"2025-04-04T20:15:42.548Z"},"accession":"S-EPMC10164352","cross_references":{"pubmed":["36857628"],"doi":["10.1161/ATVBAHA.122.318576","10.1161/atvbaha.122.318576"]}}