biostudies-literatureUnknown14Si TL<h4>Background</h4>In the summer of 2022, Macau experienced a surge of COVID-19 infections (the 618 COVID-19 wave), which had serious effects on mental health and quality of life (QoL). However, there is scant research on mental health problems and QoL among Macau residents during the 618 COVID-19 wave. This study examined the network structure of depressive symptoms (hereafter depression), and the interconnection between different depressive symptoms and QoL among Macau residents during this period.<h4>Method</h4>A cross-sectional study was conducted between 26th July and 9th September 2022. Depressive symptoms were measured with the 9-item Patient Health Questionnaire (PHQ-9), while the global QoL was measured with the two items of the World Health Organization Quality of Life-brief versFrontiers in psychology1164232https://www.ebi.ac.uk/biostudies/studies/S-EPMC10165090biostudies-literatureDepression and quality of life among Macau residents in the 2022 COVID-19 pandemic wave from the perspective of network analysis.PMC10165090Si TLChen PUngvari GSFeng YChow IHIZhang LLok KIXiang YTLi JXCheung TNg CHSu ZWang YYSha SLam MIfalseDepression and quality of life among Macau residents in the 2022 COVID-19 pandemic wave from the perspective of network analysis.<h4>Background</h4>In the summer of 2022, Macau experienced a surge of COVID-19 infections (the 618 COVID-19 wave), which had serious effects on mental health and quality of life (QoL). However, there is scant research on mental health problems and QoL among Macau residents during the 618 COVID-19 wave. This study examined the network structure of depressive symptoms (hereafter depression), and the interconnection between different depressive symptoms and QoL among Macau residents during this period.<h4>Method</h4>A cross-sectional study was conducted between 26th July and 9th September 2022. Depressive symptoms were measured with the 9-item Patient Health Questionnaire (PHQ-9), while the global QoL was measured with the two items of the World Health Organization Quality of Life-brief vers2023-01-01T00:00:00Z20232025-04-21T16:35:21.466Z2025-04-21T16:35:21.466ZS-EPMC101650903716842310.3389/fpsyg.2023.1164232