biostudies-literatureUnknown16(4)Tham EH<h4>Background and aims</h4>With an increasing number of Clinical Practice Guidelines (CPGs) addressing primary prevention of food allergy and atopic dermatitis, it is timely to undertake a comprehensive assessment of the quality and consistency of recommendations and evaluation of their implementability in different geographical settings.<h4>Methods</h4>We systematically reviewed CPGs from 8 international databases and extensive website searches. Seven reviewers screened records in any language and then used the AGREE II and AGREE REX instruments to critically appraise CPGs published between January 2011 and April 2022.<h4>Results</h4>Our search identified 2138 relevant articles, of which 30 CPGs were eventually included. Eight (27%) CPGs were shortlisted based on our predefined quality cThe World Allergy Organization journal100770https://www.ebi.ac.uk/biostudies/studies/S-EPMC10165145biostudies-literatureA systematic review of quality and consistency of clinical practice guidelines on the primary prevention of food allergy and atopic dermatitis.PMC10165145Trikamjee TEllis AKWarad VVvan Bever HLevina DBielory LWong GWKMartinez SLeung ASYvan Niekerk AYamamoto-Hanada KNavarrete ESublett JTham EHSamuel MChu DKMunblit DNorris MTang MLWallace DDahdah LfalseA systematic review of quality and consistency of clinical practice guidelines on the primary prevention of food allergy and atopic dermatitis.<h4>Background and aims</h4>With an increasing number of Clinical Practice Guidelines (CPGs) addressing primary prevention of food allergy and atopic dermatitis, it is timely to undertake a comprehensive assessment of the quality and consistency of recommendations and evaluation of their implementability in different geographical settings.<h4>Methods</h4>We systematically reviewed CPGs from 8 international databases and extensive website searches. Seven reviewers screened records in any language and then used the AGREE II and AGREE REX instruments to critically appraise CPGs published between January 2011 and April 2022.<h4>Results</h4>Our search identified 2138 relevant articles, of which 30 CPGs were eventually included. Eight (27%) CPGs were shortlisted based on our predefined quality c2023-01-01T00:00:00Z2023 Apr2025-04-21T22:39:19.838Z2025-04-05T18:52:25.068ZS-EPMC101651453716827710.1016/j.waojou.2023.100770