{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Elgersma KM"],"funding":["NINR NIH HHS"],"pubmed_abstract":["<h4>Background</h4>Infants with single ventricle (SV) congenital heart disease (CHD) undergo three staged surgeries/interventions, with risk for morbidity and mortality. We estimated the effect of human milk (HM) and direct breastfeeding (BF) on outcomes including necrotizing enterocolitis (NEC), infection-related complications, length of stay (LOS), and mortality.<h4>Methods</h4>We analyzed the National Pediatric Cardiology Quality Improvement Collaborative registry (2016-2021), examining HM/BF groups during stage 1 (S1P) and stage 2 (S2P) palliations. We calculated propensity scores for feeding exposures, then fitted Poisson and logistic regression models to compare outcomes between propensity-matched cohorts.<h4>Results</h4>Participants included 2491 infants (68 sites). Estimates for al"],"journal":["medRxiv : the preprint server for health sciences"],"pagination":["2023.04.26.23289126"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10168482"],"repository":["biostudies-literature"],"pubmed_title":["Human milk feeding and direct breastfeeding improve outcomes for infants with single ventricle congenital heart disease: Propensity score matched analysis of the NPC-QIC registry."],"pmcid":["PMC10168482"],"funding_grant_id":["F31 NR020577"],"pubmed_authors":["Georgieff MK","Spatz DL","Shah KM","Wolfson J","McKechnie AC","Elgersma KM","Fulkerson JA","Uzark K","Looman WS"],"additional_accession":[]},"is_claimable":false,"name":"Human milk feeding and direct breastfeeding improve outcomes for infants with single ventricle congenital heart disease: Propensity score matched analysis of the NPC-QIC registry.","description":"<h4>Background</h4>Infants with single ventricle (SV) congenital heart disease (CHD) undergo three staged surgeries/interventions, with risk for morbidity and mortality. We estimated the effect of human milk (HM) and direct breastfeeding (BF) on outcomes including necrotizing enterocolitis (NEC), infection-related complications, length of stay (LOS), and mortality.<h4>Methods</h4>We analyzed the National Pediatric Cardiology Quality Improvement Collaborative registry (2016-2021), examining HM/BF groups during stage 1 (S1P) and stage 2 (S2P) palliations. We calculated propensity scores for feeding exposures, then fitted Poisson and logistic regression models to compare outcomes between propensity-matched cohorts.<h4>Results</h4>Participants included 2491 infants (68 sites). Estimates for al","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Apr","modification":"2025-04-22T09:13:05.419Z","creation":"2025-04-05T22:57:05.673Z"},"accession":"S-EPMC10168482","cross_references":{"pubmed":["37162951"],"doi":["10.1101/2023.04.26.23289126"]}}